ArticleDiagnostics (Basel, Switzerland)2022
Assessment of Iodine Contrast-To-Noise Ratio in Virtual Monoenergetic Images Reconstructed from Dual-Source Energy-Integrating CT and Photon-Counting CT Data.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 47 citations in OpenAlex.
- Image-quality optimization for late iodine enhancement with photon-counting CT: impact of spectral analysis and reconstruction parameters.La Radiologia medica · 2026Article
- Follow-up recommendation rates with abdominopelvic photon counting CT: comparison with conventional dual-energy and single-energy CT.Abdominal radiology (New York) · 2026Article
- Optimal energy level of virtual monoenergetic images for iron detectability in dual-energy CT: a Phantom study.Radiological physics and technology · 2026Article
- Photon-counting CT for radiotherapy: Qualitative assessment of potential clinical value by semi-structured expert interviews.Clinical and translational radiation oncology · 2026Article
- Development and feasibility assessment of an automated, synthetic CT-guided plan selection system for bladder cancer adaptive radiotherapy: a retrospective pilot study.Translational cancer research · 2026Article
- Evaluation of ECG-Gated, High-Pitch Thoracoabdominal Angiographies With Dual-Source Photon-Counting Detector Computed Tomography.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2025Article
- Three-dimensional noise characteristics of clinical photon counting detector CT.Medical physics · 2025Article
- In Vivo Discrimination of Iodine and Tantalum-Based Liquid Embolics After Intracranial or Spinal Embolization Using Photon-Counting Detector CT.Clinical neuroradiology · 2025Article
- Photon-counting detector computed tomography: iodine density versus virtual monoenergetic imaging of pancreatic ductal adenocarcinoma.Abdominal radiology (New York) · 2025Article
- Detectability of Iodine in Mediastinal Lesions on Photon Counting CT: A Phantom Study.Diagnostics (Basel, Switzerland) · 2025Article
- Performance improvements of virtual monoenergetic images in photon-counting detector CT compared with dual source dual-energy CT: Fourier-based assessment.Physical and engineering sciences in medicine · 2025Article
- Low-contrast detectability of photon-counting-detector CT at different scan modes and image types in comparison with energy-integrating-detector CT.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Photon-counting CT: technical features and clinical impact on abdominal imaging.Abdominal radiology (New York) · 2024Review
- Investigation of abdominal artery delineation by photon-counting detector CT.La Radiologia medica · 2024Article
- Inter-reader agreement of pancreatic adenocarcinoma resectability assessment with photon counting versus energy integrating detector CT.Abdominal radiology (New York) · 2024Article
- Impact of reconstruction parameters on the accuracy of myocardial extracellular volume quantification on a first-generation, photon-counting detector CT.European radiology experimental · 2024Article
- Dual-Energy and Photon-Counting Computed Tomography in Vascular Applications-Technical Background and Post-Processing Techniques.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Optimisation of virtual monoenergetic reconstructions for the diagnosis of pulmonary embolism using photon-counting detector computed tomography angiography.Polish journal of radiology · 2024Article
- Optimal conspicuity of pancreatic ductal adenocarcinoma in virtual monochromatic imaging reconstructions on a photon-counting detector CT: comparison to conventional MDCT.Abdominal radiology (New York) · 2024Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate whether the contrast-to-noise ratio (CNR) of an iodinated contrast agent in virtual monoenergetic images (VMI) from the first clinical photon-counting detector (PCD) CT scanner is superior to VMI CNR from a dual-source dual-energy CT scanner with energy-integrating detectors (EID), two anthropomorphic phantoms in three different sizes (thorax and abdomen, QRM GmbH), in combination with a custom-built insert containing cavities filled with water, and water with 15 mg iodine/mL, were scanned on an EID-based scanner (Siemens SOMATOM Force) and on a PCD-based scanner (Siemens, NAEOTOM Alpha). VMI (range 40−100 keV) were reconstructed without an iterative reconstruction (IR) technique and with an IR strength of 60% for the EID technique (ADMIRE) and closest matching IR strengths of 50% and 75% for the PCD technique (QIR). CNR was defined as the difference in mean CT numbers of water, and water with iodine, divided by the root mean square value of the measured noise in water, and water with iodine. A two-sample t-test was performed to evaluate differences in CNR between images. A p-value < 0.05 was considered statistically significant. For VMI without IR and below 60 keV, the CNR of the PCD-based images at 120 and 90 kVp was up to 55% and 75% higher than the CNR of the EID-based images, respectively (p < 0.05). For VMI above 60 keV, CNRs of PCD-based images at both 120 and 90 kVp were up to 20% lower than the CNRs of EID-based images. Similar or improved performance of PCD-based images in comparison with EID-based images were observed for VMIs reconstructed with IR techniques. In conclusion, with PCD-CT, iodine CNR on low energy VMI (<60 keV) is better than with EID-CT.
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