Evidence map›Paper›PMID 35741275›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Machine Learning Coronary Artery Disease Prediction Based on Imaging and Non-Imaging Data.

Vassiliki I Kigka, Eleni Georga, Vassilis Tsakanikas, Savvas Kyriakidis, Panagiota Tsompou, Panagiotis Siogkas, Lampros K Michalis, Katerina K Naka, Danilo Neglia, Silvia Rocchiccioli and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Vassiliki I KigkaUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Eleni GeorgaUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Vassilis TsakanikasUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Savvas KyriakidisUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Panagiota TsompouUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Panagiotis SiogkasUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Lampros K MichalisDepartment of Cardiology, Medical School, University of Ioannina, GR 45110 Ioannina, Greece.
Katerina K NakaDepartment of Cardiology, Medical School, University of Ioannina, GR 45110 Ioannina, Greece.ORCID 0000-0002-9900-9659
Danilo NegliaFondazione Toscana Gabriele Monasterio, IT 56126 Pisa, Italy.
Silvia RocchiccioliInstitute of Clinical Physiology, National Research Council, IT 56124 Pisa, Italy.ORCID 0000-0003-3831-4200
Gualtiero PelosiInstitute of Clinical Physiology, National Research Council, IT 56124 Pisa, Italy.
Dimitrios I FotiadisUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
Antonis SakellariosUnit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, GR 45110 Ioannina, Greece.
University of Ioannina · GRIstituto di Fisiologia Clinica · ITFondazione Toscana Gabriele Monasterio · IT

Funding

Project SMARTOOL- "Simulation Modeling of coronary ARTery disease: a tool for clinical decision support " 689068
6 · The paper itself

Abstract

The prediction of obstructive atherosclerotic disease has significant clinical meaning for the decision making. In this study, a machine learning predictive model based on gradient boosting classifier is presented, aiming to identify the patients of high CAD risk and those of low CAD risk. The machine learning methodology includes five steps: the preprocessing of the input data, the class imbalance handling applying the Easy Ensemble algorithm, the recursive feature elimination technique implementation, the implementation of gradient boosting classifier, and finally the model evaluation, while the fine tuning of the presented model was implemented through a randomized search optimization of the model's hyper-parameters over an internal 3-fold cross-validation. In total, 187 participants with suspicion of CAD previously underwent CTCA during EVINCI and ARTreat clinical studies and were prospectively included to undergo follow-up CTCA. The predictive model was trained using imaging data (geometrical and blood flow based) and non-imaging data. The overall predictive accuracy of the model was 0.81, using both imaging and non-imaging data. The innovative aspect of the proposed study is the combination of imaging-based data with the typical CAD risk factors to provide an integrated CAD risk-predictive model.

Indexed as

coronary artery diseasecoronary artery disease risk stratificationmachine learning modelsnoninvasive cardiovascular imaging

Identifiers

PMID35741275
PMCPMC9221964
OpenAlexW4282912887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.