ArticleDiagnostics (Basel, Switzerland)2022
The Non-Invasive Ultrasound-Based Assessment of Liver Viscosity in a Healthy Cohort.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Multiparametric Abdominal Ultrasound as a Source of Imaging Biomarkers in Predictive and Personalized Medicine: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- A comprehensive modeling on thermal damage in tumor hyperthermia therapies using magneto-plasmonic nanocomposite.Scientific reports · 2025Article
- Sound Touch Viscosity (STVi) for Thyroid Gland Evaluation in Healthy Individuals: A Pilot Study : STVi for Thyroid Gland Evaluation.Current medical imaging · 2025Article
- Shear Wave Dispersion Elastography in ALD and MASLD: Comparative Pathophysiology and Clinical Potential-A Narrative Review.Journal of clinical medicine · 2024Review
- Kidney cortex shear wave motion simulations based on segmented biopsy histology.Computer methods and programs in biomedicine · 2024Article
- Shear Wave Dispersion in Chronic Liver Disease: From Physical Principles to Clinical Usefulness.Journal of personalized medicine · 2023Review
- Article
- Quantification of Thyroid Viscosity in Healthy Subjects Using Ultrasound Shear Wave Dispersion (Viscosity PLUS).Diagnostics (Basel, Switzerland) · 2022Article
- Viscoelasticity during development: What is it? and why should you care?Seminars in cell & developmental biologyReview
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver fibrosis is the most significant prognostic factor in chronic liver disease (CLD). Clinical practice guidelines recommend the use of non-invasive techniques, such as two-dimensional shear-wave elastography (2D-SWE), to assess liver stiffness as a marker of fibrosis. Several other factors influence liver stiffness in addition to liver fibrosis. It is presumed that changes due to necro-inflammation modify the propagation of shear waves (dispersion). Therefore, new imaging techniques that investigate the dispersion properties of shear waves have been developed, which can serve as an indirect method of measuring liver viscosity (Vi PLUS). Defining the reference values in healthy subjects among different age groups and genders and analyzing the factors that influence these values is essential. However, published data on liver viscosity are still limited. This is the first study that aimed to assess the normal range of liver viscosity values in subjects with healthy livers and analyze the factors that influence them. One hundred and thirty-one consecutive subjects with healthy livers were enrolled in this prospective study. The results showed that Vi PLUS is a highly feasible method. Liver stiffness, age and BMI influenced the liver viscosity values. The mean liver viscosity by Vi PLUS in subjects with healthy livers was 1.59 Pa·s.
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