Evidence map›Paper›PMID 35741251›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine.

Matthias Michael Woeltjen, Julius Henning Niehoff, Arwed Elias Michael, Sebastian Horstmeier, Christoph Moenninghoff, Jan Borggrefe, Jan Robert Kroeger

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Matthias Michael WoeltjenDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.ORCID 0000-0001-7624-5109
Julius Henning NiehoffDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.
Arwed Elias MichaelDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.
Sebastian HorstmeierDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.ORCID 0000-0001-5352-0059
Christoph MoenninghoffDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.
Jan BorggrefeDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.ORCID 0000-0003-2908-7560
Jan Robert KroegerDepartment of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.ORCID 0000-0003-1218-7610
University Hospitals of the Ruhr-University of Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the qualitative and quantitative image quality of low-dose high-resolution (LD-HR) lung CT scans acquired with the first clinical approved photon counting CT (PCCT) scanner. Furthermore, the radiation dose used by the PCCT is compared to a conventional CT scanner with an energy-integrating detector system (EID-CT). Twenty-nine patients who underwent a LD-HR chest CT scan with dual-source PCCT and had previously undergone a LD-HR chest CT with a standard EID-CT scanner were retrospectively included in this study. Images of the whole lung as well as enlarged image sections displaying a specific finding (lesion) were evaluated in terms of overall image quality, image sharpness and image noise by three senior radiologists using a 5-point Likert scale. The PCCT images were reconstructed with and without a quantum iterative reconstruction algorithm (PCCT QIR+/−). Noise and signal-to-noise (SNR) were measured and the effective radiation dose was calculated. Overall, image quality and image sharpness were rated best in PCCT (QIR+) images. A significant difference was seen particularly in image sections of PCCT (QIR+) images compared to EID-CT images (p < 0.005). Image noise of PCCT (QIR+) images was significantly lower compared to EID-CT images in image sections (p = 0.005). In contrast, noise was lowest on EID-CT images (p < 0.001). The PCCT used significantly less radiation dose compared to the EID-CT (p < 0.001). In conclusion, LD-HR PCCT scans of the lung provide better image quality while using significantly less radiation dose compared to EID-CT scans.

Indexed as

computed tomographyCTLD-HR CTlow dose chest CTlow dose lung CTPCCT vs. EIDphoton counting detector

Identifiers

PMID35741251
PMCPMC9221815
OpenAlexW4282972377

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.