Evidence map›Paper›PMID 35741140›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Evaluation of a Maternal Plasma RNA Panel Predicting Spontaneous Preterm Birth and Its Expansion to the Prediction of Preeclampsia.

Carl Philip Weiner, Howard Cuckle, Mark Louis Weiss, Irina Alexandra Buhimschi, Yafeng Dong, Helen Zhou, Risa Ramsey, Robert Egerman, Catalin Sorin Buhimschi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06385366 (Developing and Evaluating Models for Early Prediction of Obstetrical Diseases), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06385366 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Developing and Evaluating Models for Early Prediction of Obstetrical Diseases: Preeclampsia, Spontaneous Preterm Birth, and Gestational Diabetes in The Pregnant Women Performed Non-invasive Prenatal Screening (NIPT)

TypeobservationalSponsorGene SolutionsRan2024 to 2025Enrolled1,105ConditionsPregnant With Complication, Preeclampsia, Preterm Birth, Gestational Diabetes
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. [Latest Research Findings on Prediction of Preeclampsia in Pregnant Women Based on Analysis of Cell-Free RNA in Peripheral Blood].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Carl Philip WeinerDepartment of Obstetrics and Gynecology, Kansas University Medical Center, Kansas City, KS 66160, USA.ORCID 0000-0002-1044-9026
Howard CuckleFaculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 6934206, Israel.ORCID 0000-0003-2450-2403
Mark Louis WeissDepartments of Anatomy and Physiology & Midwest Institute of Comparative Stem Cell Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-4647-7619
Irina Alexandra BuhimschiDepartment of Obstetrics and Gynecology, University of Illinois-Chicago, Chicago, IL 60612, USA.
Yafeng DongDepartment of Obstetrics and Gynecology, Kansas University Medical Center, Kansas City, KS 66160, USA.
Helen ZhouDepartment of Obstetrics and Gynecology, Kansas University Medical Center, Kansas City, KS 66160, USA.
Risa RamseyOffice of Clinical Research, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Robert EgermanDepartment of Obstetrics and Gynecology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2063-7765
Catalin Sorin BuhimschiDepartment of Obstetrics and Gynecology, University of Illinois-Chicago, Chicago, IL 60612, USA.
University Medical Center · USUniversity of Illinois Chicago · USKansas State University · USTel Aviv University · ILUniversity of Florida · USUniversity of Tennessee Health Science Center · US

Funding

CDC HHS U01 DP000187, 2005-2010NCCDPHP CDC HHS U01 DP000187Wellcome Trust
6 · The paper itself

Abstract

Preterm birth is the principal contributor to neonatal death and morbidity worldwide. We previously described a plasma cell-free RNA panel that between 16 and 20 weeks of pregnancy had potential to predict spontaneous preterm birth (sPTB) ≤ 32 weeks caused by preterm labor (PTL) or preterm premature rupture of membranes (PPROM). The present study had three objectives:

Indexed as

early onset preeclampsiaextreme prematurityplasma RNAplasma transcriptomepreeclampsiapreterm birthpreterm laborprognosticationscreening

Identifiers

PMID35741140
PMCPMC9221694
OpenAlexW4282050004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.