Evidence map›Paper›PMID 35740868›Full record

ArticleBiomolecules2022

Glycome Profiling of Cancer Cell Lines Cultivated in Physiological and Commercial Media.

Junyao Wang, Wenjing Peng, Aiying Yu, Mohamed Fokar, Yehia Mechref

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Journal of proteome research · 2024
    Article
  2. An Efficient and EconomicalMetabolites · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Junyao WangDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-7614-5615
Wenjing PengDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Aiying YuDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-3323-8184
Mohamed FokarCenter of Biotechnology and Genomics, Texas Tech University, Lubbock, TX 79409, USA.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-6661-6073
Texas Tech University · US

Funding

Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
Illumina NovaSeq 6000 DNA Sequencing SystemS10OD025115 · OD · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2018 to 2018
$594k
NIGMS NIH HHS R01 GM112490NIGMS NIH HHS R01 GM130091NIH HHS 1R01GM112490-08NIH HHS 1R01GM130091-04NIH HHS 1S10OD025115-01NIH HHS S10 OD025115
6 · The paper itself

Abstract

A complex physiological culture medium (Plasmax) was introduced recently, composed of nutrients and metabolites at concentrations normally found in human plasma to mimic the in vivo environment for cell line cultivation. As glycosylation has been proved to be involved in cancer development, it is necessary to investigate the glycan expression changes in media with different nutrients. In this study, a breast cancer cell line, MDA-MB-231BR, and a brain cancer cell line, CRL-1620, were cultivated in Plasmax and commercial media to reveal cell line glycosylation discrepancies prompted by nutritional environments. Glycomics analyses of cell lines were performed using LC-MS/MS. The expressions of multiple fucosylated

Indexed as

Brain NeoplasmsTandem Mass SpectrometryCell LineChromatography, LiquidHumansPolysaccharidesPolysaccharidescancer cell lineculturing mediadifferential expression analysisglycomicsLC-MS/MS

Identifiers

PMID35740868
PMCPMC9221004
OpenAlexW4281488793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.