Evidence map›Paper›PMID 35740795›Full record

ArticleChildren (Basel, Switzerland)2022

Long-Term Outcomes of Congenital Diaphragmatic Hernia: Report of a Multicenter Study in Japan.

Masaya Yamoto, Kouji Nagata, Keita Terui, Masahiro Hayakawa, Hiroomi Okuyama, Shoichiro Amari, Akiko Yokoi, Kouji Masumoto, Tadaharu Okazaki, Noboru Inamura and 5 more

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Masaya YamotoDepartment of Pediatric Surgery, Shizuoka Children's Hospital, Shizuoka 420-8660, Japan.ORCID 0000-0001-6660-362X
Kouji NagataDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka 812-8582, Japan.ORCID 0000-0002-8933-8889
Keita TeruiDepartment of Pediatric Surgery, Chiba University Graduate School of Medicine, Chiba 260-867, Japan.ORCID 0000-0003-4315-5179
Masahiro HayakawaDivision of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya 466-8560, Japan.ORCID 0000-0001-5217-3219
Hiroomi OkuyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.
Shoichiro AmariDivision of Neonatology, National Center for Child Health and Development, Tokyo 157-0074, Japan.ORCID 0000-0003-4750-513X
Akiko YokoiDepartment of Pediatric Surgery, Kobe Children's Hospital, Kobe 650-0047, Japan.
Kouji MasumotoDepartment of Pediatric Surgery, Tsukuba University, Tsukuba 305-8577, Japan.
Tadaharu OkazakiDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, Urayasu 279-0021, Japan.
Noboru InamuraDepartment of Pediatrics, Kindai University Faculty of Medicine, Osaka-Sayama 589-0014, Japan.
Katsuaki ToyoshimaDepartment of Neonatology, Kanagawa Children's Medical Center, Yokohama 232-8555, Japan.
Yuhki KoikeDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Yuta YazakiDepartment of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Taizo FurukawaDepartment of Pediatric Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Noriaki UsuiDepartment of Pediatric Surgery, Osaka Women's and Children's Hospital, Izumi 594-1101, Japan.

Funding

The Ministry of Health, Labour, and Welfare of Japan 20FC1017
6 · The paper itself

Abstract

backgroundTreatment modalities for neonates with congenital diaphragmatic hernia (CDH) have greatly improved in recent years, with a concomitant increase in survival. However, long-term outcomes restrict the identification of optimal care pathways for CDH survivors in adolescence and adulthood. Therefore, we evaluated the long-term outcomes within the Japanese CDH Study Group (JCDHSG).

methodsParticipants were born with CDH between 2006 and 2018 according to the JCDHSG. Participants were enrolled in the database at 1.5, 3, 6, and 12 years old. Follow-up items included long-term complications, operations for long-term complication, and home medical care.

resultsA total of 747 patients were included in this study, with 626 survivors (83.8%) and 121 non-survivors (16.2%). At 1.5, 3, 6, and 12 years old, 45.4%, 36.5%, 34.8%, and 43.6% developed complications, and 20.1%, 14.7%, 11.5%, and 5.1% of participants required home care, respectively. Recurrence, pneumonia, pneumothorax, gastroesophageal reflux disease, and intestinal obstruction decreased with age, and thoracic deformity increased with age.

conclusionsAs CDH survival rates improve, there is a need for continued research and fine-tuning of long-term care to optimize appropriate surveillance and long-term follow-up.

Indexed as

congenital diaphragmatic herniagastroesophageal reflux diseaseintestinal obstructionlong-term outcomespneumoniapneumothoraxrecurrence

Identifiers

PMID35740795
PMCPMC9222080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.