Evidence map›Paper›PMID 35740789›Full record

ArticleChildren (Basel, Switzerland)2022

Lower Respiratory Tract Infections in Pediatric Patients with Severe Neurological Impairments: Clinical Observations and Perspectives in a Palliative Care Unit.

Maximilian David Mauritz, Carola Hasan, Pia Schmidt, Arne Simon, Markus Knuf, Boris Zernikow

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maximilian David MauritzPaediatric Palliative Care Centre, Children's and Adolescents' Hospital, Witten/Herdecke University, 58448 Witten, Germany.ORCID 0000-0002-9618-5307
Carola HasanPaediatric Palliative Care Centre, Children's and Adolescents' Hospital, Witten/Herdecke University, 58448 Witten, Germany.
Pia SchmidtPaediatric Palliative Care Centre, Children's and Adolescents' Hospital, Witten/Herdecke University, 58448 Witten, Germany.
Arne SimonPediatric Oncology and Hematology, University Hospital Homburg Saar, 66421 Homburg, Germany.ORCID 0000-0001-9558-3330
Markus KnufDepartment for Pediatric and Adolescent Medicine, Worms Clinic, 67550 Worms, Germany.
Boris ZernikowPaediatric Palliative Care Centre, Children's and Adolescents' Hospital, Witten/Herdecke University, 58448 Witten, Germany.ORCID 0000-0001-5875-3775
Witten/Herdecke University · DEUniversity of Applied Sciences Worms · DE

Funding

Federal Ministry of Education and Research 01GY1713
6 · The paper itself

Abstract

Pediatric palliative care (PPC) patients with a severe neurologic impairment (SNI) suffer considerable morbidity and increased mortality from lower respiratory tract infections (LRTIs). The indication and choice of antibiotic therapy for bacterial LRTIs are often challenging given the lack of evidence-based treatment recommendations for this vulnerable patient population. We conducted an observational study before the SARS-CoV-2 pandemic in an eight-bed pediatric palliative care inpatient unit. During two years of surveillance, we diagnosed and treated 33 cases of a bacterial LRTI in patients with an SNI; 5 patients were hospitalized with an LRTI more than once. Two patients died from complications due to LRTIs during hospitalization. Three patients (15%) were colonized with multidrug-resistant organisms. An initial antibiotic treatment failed in one-third of the cases; a successful therapy of the LRTI was achieved with broad-spectrum and extended-spectrum penicillins (

Indexed as

adolescentschildrenchildren with medical complexitylower respiratory tract infectionpediatric palliative carepneumoniasevere neurological impairment

Identifiers

PMID35740789
PMCPMC9221664
OpenAlexW4281730664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.