Evidence map›Paper›PMID 35740644›Full record

ArticleCancers2022

Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer.

Céline Lecointre, Elise Fourgous, Ingrid Montarras, Clément Kerneur, Valérie Simon, Yvan Boublik, Débora Bonenfant, Bruno Robert, Pierre Martineau, Serge Roche

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Céline LecointreCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.
Elise FourgousCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.ORCID 0000-0002-3626-250X
Ingrid MontarrasCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.
Clément KerneurCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.ORCID 0000-0002-9168-078X
Valérie SimonCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.
Yvan BoublikCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.
Débora BonenfantNovartis Institutes for BioMedical Research, CH 4033 Basel, Switzerland.
Bruno RobertIRCM, INSERM, University of Montpellier, 34000 Montpellier, France.
Pierre MartineauIRCM, INSERM, University of Montpellier, 34000 Montpellier, France.ORCID 0000-0002-7993-7183
Serge RocheCRBM, University of Montpellier, CNRS, 34000 Montpellier, France.ORCID 0000-0003-3413-3859
Centre National de la Recherche Scientifique · FRInserm · FRNovartis (Switzerland) · CH

Funding

Fondation pour la Recherche Médicale espoir de la rechercheFrench National Cancer Institute INCa-DGOS-Inserm 6045French National Cancer Institute PLBIO-2011-150Ligue Nationale Contre le Cancer Equipe labellisée 2020
6 · The paper itself

Abstract

The PEAK family pseudokinases are essential components of tyrosine kinase (TK) pathways that regulate cell growth and adhesion; however, their role in human cancer remains unclear. Here, we report an oncogenic activity of the pseudokinase PEAK2 in colorectal cancer (CRC). Notably, high

Indexed as

actin cytoskeletoncell migrationcell signallingcolorectal canceroncogenephosphoproteomicpseudokinase

Identifiers

PMID35740644
PMCPMC9221080
OpenAlexW4283068119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.