Evidence map›Paper›PMID 35740588›Full record

ArticleCancers2022

Analysis of Cross-Combinations of Feature Selection and Machine-Learning Classification Methods Based on [

Ober Van Gómez, Joaquin L Herraiz, José Manuel Udías, Alexander Haug, Laszlo Papp, Dania Cioni, Emanuele Neri

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  11. Robust vs. Non-robust radiomic features: the quest for optimal machine learning models using phantom and clinical studies.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  12. Article
  13. Article
  14. ExplainableJournal of cancer research and clinical oncology · 2024
    Article
  15. Clinical application ofJapanese journal of radiology · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. OptimalFrontiers in oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ober Van GómezNuclear Physics Group and IPARCOS, Faculty of Physical Sciences, University Complutense of Madrid, CEI Moncloa, 28040 Madrid, Spain.ORCID 0000-0003-1411-6197
Joaquin L HerraizNuclear Physics Group and IPARCOS, Faculty of Physical Sciences, University Complutense of Madrid, CEI Moncloa, 28040 Madrid, Spain.ORCID 0000-0001-7208-8863
José Manuel UdíasNuclear Physics Group and IPARCOS, Faculty of Physical Sciences, University Complutense of Madrid, CEI Moncloa, 28040 Madrid, Spain.
Alexander HaugDivision of Nuclear Medicine, Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-8308-6174
Laszlo PappCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-9049-9989
Dania CioniAcademic Radiology and Master in Oncologic Imaging, Department of Translational Research, University of Pisa, Via Roma, 67, 56126 Pisa, Italy.ORCID 0000-0002-5120-886X
Emanuele NeriAcademic Radiology and Master in Oncologic Imaging, Department of Translational Research, University of Pisa, Via Roma, 67, 56126 Pisa, Italy.ORCID 0000-0001-7950-4559
University of Pisa · ITMedical University of Vienna · ATUniversidad Complutense de Madrid · ES

Funding

Smart and self-reporting clinical nano carriers for drug deliveryR01CA215700 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2017 to 2021
$3.5M
NCI NIH HHS R01 CA215700
6 · The paper itself

Abstract

backgroundThis study aimed to identify optimal combinations between feature selection methods and machine-learning classifiers for predicting the metabolic response of individual metastatic breast cancer lesions, based on clinical variables and radiomic features extracted from pretreatment [

methodsA total of 48 patients with confirmed metastatic breast cancer, who received different treatments, were included. All patients had an [

resultsThe combinations, least absolute shrinkage and selection operator (Lasso) + support vector machines (SVM), or random forest (RF) had the highest AUC in the cross-validation, with 0.93 ± 0.06 and 0.92 ± 0.03, respectively, whereas Lasso + neural network (NN) or SVM, and mutual information (MI) + RF, had the higher AUC and ACC in the validation cohort, with 0.90/0.72, 0.86/0.76, and 87/85, respectively. On average, the models with Lasso and models with SVM had the best mean performance for both AUC and ACC in both training and validation cohorts.

conclusionsImage features obtained from a pretreatment [

Indexed as

FDG-PET/CTfeature selectionheterogeneous metabolic responsesmachine learningmetabolic responsemetastatic breast cancerradiomics

Identifiers

PMID35740588
PMCPMC9221062
OpenAlexW4282928821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.