Evidence map›Paper›PMID 35740563›Full record

ReviewCancers2022

Bias and Class Imbalance in Oncologic Data-Towards Inclusive and Transferrable AI in Large Scale Oncology Data Sets.

Erdal Tasci, Ying Zhuge, Kevin Camphausen, Andra V Krauze

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erdal TasciCenter for Cancer Research, National Cancer Institute, NIH, Building 10, Bethesda, MD 20892, USA.ORCID 0000-0001-6754-2187
Ying ZhugeCenter for Cancer Research, National Cancer Institute, NIH, Building 10, Bethesda, MD 20892, USA.
Kevin CamphausenCenter for Cancer Research, National Cancer Institute, NIH, Building 10, Bethesda, MD 20892, USA.
Andra V KrauzeCenter for Cancer Research, National Cancer Institute, NIH, Building 10, Bethesda, MD 20892, USA.

Funding

Radiation Oncology Branch - Radiation ClinicZIDBC010990 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CAMPHAUSEN, KEVIN · 2009 to 2025
$136.0M
Pre-clinical Development of Radiation Sensitizers for Patients with GlioblastomaZIASC010372 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI CAMPHAUSEN, KEVIN · 2009 to 2025
$12.0M
Radiation Oncology Branch - Radiation ClinicZ01BC010990 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CAMPHAUSEN, KEVIN · 2008 to 2008
$4.8M
Prognostic and predictive clinical and proteomic biomarker discovery in GBMZIABC012094 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRAUZE, ANDRA · 2022 to 2025
$847k
Generating a multi-channel data framework for AI analysis in Radiation therapyZIABC012095 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRAUZE, ANDRA · 2022 to 2025
$847k
Advancing clinically meaningful AI algorithms to improve oncologic outcomesZIABC012096 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRAUZE, ANDRA · 2022 to 2025
$847k
Proteogenomic characterization and biomarker discovery in glioblastomaZIABC012093 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRAUZE, ANDRA · 2022 to 2025
$847k
Using artificial intelligence and MRI to address limitations in glioblastomaZIABC012092 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRAUZE, ANDRA · 2022 to 2025
$847k
Intramural NIH HHS Z01 BC010990Intramural NIH HHS ZID BC010990NCI NIH HHS ZID BC 010990
6 · The paper itself

Abstract

Recent technological developments have led to an increase in the size and types of data in the medical field derived from multiple platforms such as proteomic, genomic, imaging, and clinical data. Many machine learning models have been developed to support precision/personalized medicine initiatives such as computer-aided detection, diagnosis, prognosis, and treatment planning by using large-scale medical data. Bias and class imbalance represent two of the most pressing challenges for machine learning-based problems, particularly in medical (e.g., oncologic) data sets, due to the limitations in patient numbers, cost, privacy, and security of data sharing, and the complexity of generated data. Depending on the data set and the research question, the methods applied to address class imbalance problems can provide more effective, successful, and meaningful results. This review discusses the essential strategies for addressing and mitigating the class imbalance problems for different medical data types in the oncologic domain.

Indexed as

artificial intelligenceclass imbalanceclinical datamachine learningoncology

Identifiers

PMID35740563
PMCPMC9221277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.