Evidence map›Paper›PMID 35740548›Full record

ArticleCancers2022

A Fraction of CD8+ T Cells from Colorectal Liver Metastases Preferentially Repopulate Autologous Patient-Derived Xenograft Tumors as Tissue-Resident Memory T Cells.

Frank Liang, Lisa M Nilsson, Fabian Byvald, Azar Rezapour, Helena Taflin, Jonas A Nilsson, Ulf Yrlid

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Frank LiangDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0003-3675-3816
Lisa M NilssonSahlgrenska Translational Melanoma Group, Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, 40530 Gothenburg, Sweden.
Fabian ByvaldDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0003-0516-5448
Azar RezapourDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.
Helena TaflinDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska University Hospital, University of Gothenburg, 41345 Gothenburg, Sweden.
Jonas A NilssonSahlgrenska Translational Melanoma Group, Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0003-0346-6837
Ulf YrlidDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0002-3431-6770
University of Gothenburg · SEThe University of Western Australia · AUSahlgrenska University Hospital · SE

Funding

Swedish Cancer Society 2018/652Swedish Cancer Society 2018/724Swedish Society of Medical Research P17-0024The Sjöberg Foundation 2020-160The Swedish State under the agreement between Swedish government and the county councils- the ALF agreement ALFGBG-719301The Swedish State under the agreement between Swedish government and the county councils- the ALF agreement ALFGBG-723231
6 · The paper itself

Abstract

The diversity of T cells in the human liver may reflect the composition of TILs in CRLM. Our ex vivo characterization of CRLM vs. adjacent liver tissue detected CD103+CD39+CD8+ T

Indexed as

colorectal liver metastasesMEK inhibitionpatient-derived xenograft modeltissue-resident memory T cellstumor-infiltrating lymphocytes

Identifiers

PMID35740548
PMCPMC9221137
OpenAlexW4282557898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.