Evidence map›Paper›PMID 35740541›Full record

ReviewCancers2022

The Mycobiome: Cancer Pathogenesis, Diagnosis, and Therapy.

Ahmed Gamal, Mohammed Elshaer, Mayyadah Alabdely, Ahmed Kadry, Thomas S McCormick, Mahmoud Ghannoum

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Biomedicines · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed GamalDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0001-7215-4445
Mohammed ElshaerDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0002-0179-2869
Mayyadah AlabdelyDepartment of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Ahmed KadryDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.
Thomas S McCormickDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.
Mahmoud GhannoumDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.

Funding

Polymicrobial interactions in Crohn's DiseaseR01AI145289 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI GHANNOUM, MAHMOUD A · 2019 to 2023
$3.1M
NIAID NIH HHS R01 AI145289NIH HHS R01AI145289- 01A1
6 · The paper itself

Abstract

Cancer is among the leading causes of death globally. Despite advances in cancer research, a full understanding of the exact cause has not been established. Recent data have shown that the microbiome has an important relationship with cancer on various levels, including cancer pathogenesis, diagnosis and prognosis, and treatment. Since most studies have focused only on the role of bacteria in this process, in this article we review the role of fungi-another important group of the microbiome, the totality of which is referred to as the "mycobiome"-in the development of cancer and how it can impact responses to anticancer medications. Furthermore, we provide recent evidence that shows how the different microbial communities interact and affect each other at gastrointestinal and non-gastrointestinal sites, including the skin, thereby emphasizing the importance of investigating the microbiome beyond bacteria.

Indexed as

anticancercancercancer pathogenesiscancer therapyfungimycobiome

Identifiers

PMID35740541
PMCPMC9221014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.