Evidence map›Paper›PMID 35740537›Full record

ArticleCancers2022

A Laboratory-Friendly CTC Identification: Comparable Double-Immunocytochemistry with Triple-Immunofluorescence.

Raed Sulaiman, Pradip De, Jennifer C Aske, Xiaoqian Lin, Adam Dale, Ethan Vaselaar, Nischal Koirala, Cheryl Ageton, Kris Gaster, Joshua Plorde and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. American journal of cancer research · 2024
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Raed SulaimanPhysicians Laboratory, Department of Pathology, Avera McKennan Hospital & University Health Center, Sioux Falls, SD 57105, USA.
Pradip DeTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.
Jennifer C AskeTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.ORCID 0000-0001-9405-5464
Xiaoqian LinTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.
Adam DaleTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.
Ethan VaselaarTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.
Nischal KoiralaTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.
Cheryl AgetonDepartment of Research Oncology, Clinical Research, Sioux Falls, SD 57105, USA.
Kris GasterAvera Cancer Institute, Avera McKennan Hospital, Sioux Falls, SD 57105, USA.
Joshua PlordeDiagnostic Radiology, Interventional Radiology, and Radiology, Avera Medical Group Radiology, Sioux Falls, SD 57105, USA.
Benjamin SolomonHematology and Oncology, Avera Medical Group Oncology & Hematology, Sioux Falls, SD 57105, USA.
Bradley ThaemertBariatrics, Surgery, and General Surgery, Surgical Institute of South Dakota, Sioux Falls, SD 57105, USA.
Paul MeyerCardiovascular/Thoracic Surgery, Surgery North Central Heart, A Division of Avera Heart Hospital, Sioux Falls, SD 57105, USA.
Luis Rojas EspaillatDepartment of Gynecologic Oncology, Avera Cancer Institute, Sioux Falls, SD 57105, USA.
David StarksDepartment of Gynecologic Oncology, Avera Cancer Institute, Sioux Falls, SD 57105, USA.
Nandini DeyTranslational Oncology Laboratory, Avera Research Institute, Sioux Falls, SD 57105, USA.ORCID 0000-0002-5533-8784
Avera Health · USAvera McKennan Hospital & University Health Center · USUniversity of South Dakota · USAvera Heart Hospital · USSanford Research · US

Funding

Avera McKennan Hospital & University Health Center NA
6 · The paper itself

Abstract

The source of circulating tumor cells (CTC) in the peripheral blood of patients with solid tumors are from primary cancer, metastatic sites, and a disseminated tumor cell pool. As 90% of cancer-related deaths are caused by metastatic progression and/or resistance-associated treatment failure, the above fact justifies the undeniable predictive and prognostic value of identifying CTC in the bloodstream at stages of the disease progression and resistance to treatment. Yet enumeration of CTC remains far from a standard routine procedure either for post-surgery follow-ups or ongoing adjuvant therapy. The most compelling explanation for this paradox is the absence of a convenient, laboratory-friendly, and cost-effective method to determine CTC. We presented a specific and sensitive laboratory-friendly

Indexed as

CTCimmunocytochemistrylaboratory-friendlyparallel double-detection

Identifiers

PMID35740537
PMCPMC9221448
OpenAlexW4281710077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.