Evidence map›Paper›PMID 35740503›Full record

ReviewCancers2022

Synthetic Vulnerabilities in the KRAS Pathway.

Marta Roman, Elizabeth Hwang, E Alejandro Sweet-Cordero

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Structure-Selective Polydopamine Coating on Drug Nanoparticles.ACS applied materials & interfaces · 2026
    Article
  2. KRAS Inhibition in Pancreatic Ductal Adenocarcinoma.Journal of clinical medicine · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marta RomanDepartment of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-1752-018X
Elizabeth HwangDepartment of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA.
E Alejandro Sweet-CorderoDepartment of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA.
University of California, San Francisco · US

Funding

Identifying and Targeting Mechanisms for Membrane Signaling in Human CancerR01CA250534 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACKSON, PETER KENT, SWEET-CORDERO, ERIC ALEJANDRO · 2021 to 2025
$2.7M
Fundación Ramón Areces XXXII CallNCI NIH HHS R01 CA250534NCI NIH HHS R01 CA250534-01A1
6 · The paper itself

Abstract

Mutations in

Indexed as

cancerKRASsynthetic lethality

Identifiers

PMID35740503
PMCPMC9221492
OpenAlexW4281746739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.