Evidence map›Paper›PMID 35740475›Full record

ArticleBiomedicines2022

Maria V Golikova, Kamilla N Alieva, Alla V Filimonova, Vladimir A Ageevets, Ofeliia S Sulian, Alisa A Avdeeva, Sergey V Sidorenko, Stephen H Zinner

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Maria V GolikovaDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya Street, 119021 Moscow, Russia.ORCID 0000-0002-7588-1733
Kamilla N AlievaDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya Street, 119021 Moscow, Russia.
Alla V FilimonovaDepartment of Pharmacokinetics & Pharmacodynamics, Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya Street, 119021 Moscow, Russia.
Vladimir A AgeevetsPediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popov Street, 197022 Saint Petersburg, Russia.
Ofeliia S SulianPediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popov Street, 197022 Saint Petersburg, Russia.
Alisa A AvdeevaPediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popov Street, 197022 Saint Petersburg, Russia.
Sergey V SidorenkoPediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popov Street, 197022 Saint Petersburg, Russia.ORCID 0000-0003-3550-7875
Stephen H ZinnerHarvard Medical School, Department of Medicine, Mount Auburn Hospital, 330 Mount Auburn St., Cambridge, MA 02138, USA.ORCID 0000-0002-9917-446X
Gause Institute of New Antibiotics Russian Academy of Medical Sciences · RUMount Auburn Hospital · USNorth-Western State Medical University named after I.I. Mechnikov · RU

Funding

Russian Science Foundation 21-74-10090
6 · The paper itself

Abstract

The inoculum effect (IE) is a well-known phenomenon with beta-lactams. At the same time, the IE has not been extensively studied with carbapenem/carbapenemase inhibitor combinations. The antibiotic-to-inhibitor concentration ratio used in susceptibility testing can influence the in vitro activity of the combination. To explore the role of these factors, imipenem/relebactam and doripenem/relebactam MICs were estimated against six

Indexed as

beta-lactamase inhibitorsbeta-lactamsdoripenemimipeneminoculum effectKlebsiella pneumoniaerelebactam

Identifiers

PMID35740475
PMCPMC9221057
OpenAlexW4283217312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.