Evidence map›Paper›PMID 35740402›Full record

ReviewBiomedicines2022

Emerging Prospects of Nanozymes for Antibacterial and Anticancer Applications.

Nayanika Chakraborty, Sona Gandhi, Rajni Verma, Indrajit Roy

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. WSeAnalytical and bioanalytical chemistry · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Ultrafast synthesis of L-His-FeFrontiers in bioengineering and biotechnology · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Preparation and Application of Carbon Dots Nanozymes.Antioxidants (Basel, Switzerland) · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nayanika ChakrabortyDepartment of Chemistry, University of Delhi, Delhi 110007, India.
Sona GandhiDepartment of Chemistry, University of Delhi, Delhi 110007, India.
Rajni VermaSchool of Physics, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, Australia.
Indrajit RoyDepartment of Chemistry, University of Delhi, Delhi 110007, India.
University of Delhi · INGalgotias University · INUniversity of Melbourne · AU

Funding

Council of Scientific and Industrial Research, India CSIRInstitute of Eminence, University of Delhi, India IoEMckenzie Fellowship, University of Melbourne, Australia Mckenzie
6 · The paper itself

Abstract

The ability of some nanoparticles to mimic the activity of certain enzymes paves the way for several attractive biomedical applications which bolster the already impressive arsenal of nanomaterials to combat deadly diseases. A key feature of such 'nanozymes' is the duplication of activities of enzymes or classes of enzymes, such as catalase, superoxide dismutase, oxidase, and peroxidase which are known to modulate the oxidative balance of treated cells for facilitating a particular biological process such as cellular apoptosis. Several nanoparticles that include those of metals, metal oxides/sulfides, metal-organic frameworks, carbon-based materials, etc., have shown the ability to behave as one or more of such enzymes. As compared to natural enzymes, these artificial nanozymes are safer, less expensive, and more stable. Moreover, their catalytic activity can be tuned by changing their size, shape, surface properties, etc. In addition, they can also be engineered to demonstrate additional features, such as photoactivated hyperthermia, or be loaded with active agents for multimodal action. Several researchers have explored the nanozyme-mediated oxidative modulation for therapeutic purposes, often in combination with other diagnostic and/or therapeutic modalities, using a single probe. It has been observed that such synergistic action can effectively by-pass the various defense mechanisms adapted by rogue cells such as hypoxia, evasion of immuno-recognition, drug-rejection, etc. The emerging prospects of using several such nanoparticle platforms for the treatment of bacterial infections/diseases and cancer, along with various related challenges and opportunities, are discussed in this review.

Indexed as

antibacterial therapyanticancer therapyenzyme mimicsnanozymereactive oxygen species

Identifiers

PMID35740402
PMCPMC9219663
OpenAlexW4281718840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.