Evidence map›Paper›PMID 35740316›Full record

ArticleBiomedicines2022

Ultra-Fine Polyethylene Hernia Meshes Improve Biocompatibility and Reduce Intraperitoneal Adhesions in IPOM Position in Animal Models.

Marius J Helmedag, Daniel Heise, Roman M Eickhoff, Sophia M Schmitz, Mare Mechelinck, Caroline Emonts, Tim Bolle, Thomas Gries, Ulf Peter Neumann, Christian Daniel Klink and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marius J HelmedagDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.ORCID 0000-0002-8914-7978
Daniel HeiseDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.ORCID 0000-0001-6923-0849
Roman M EickhoffDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Sophia M SchmitzDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.ORCID 0000-0001-6732-1595
Mare MechelinckDepartment of Anesthesiology, Uniklinik RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-8928-338X
Caroline EmontsInstitut für Textiltechnik, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-6252-8351
Tim BolleInstitut für Textiltechnik, RWTH Aachen University, 52074 Aachen, Germany.
Thomas GriesInstitut für Textiltechnik, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-2480-8333
Ulf Peter NeumannDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Christian Daniel KlinkDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Andreas LambertzDepartment of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
RWTH Aachen University · DEUniversitätsklinikum Aachen · DE

Funding

ITA technology transfer GmbH N/A
6 · The paper itself

Abstract

(1) Introduction: The intraperitoneal onlay mesh technique (IPOM) is widely used to repair incisional hernias. This method has advantages but suffers from complications due to intraperitoneal adhesion formation between the mesh and intestine. An ideal mesh minimizes adhesions and shows good biocompatibility. To address this, newly developed multifilamentous polyethylene (PET) meshes were constructed from sub-macrophage-sized monofilaments and studied regarding biocompatibility and adhesion formation. (2) Methods: We investigated fine (FPET, 72 filaments, 11 µm diameter each) and ultra-fine multifilament (UFPET, 700 filaments, 3 µm diameter each) polyethylene meshes for biocompatibility in subcutaneous implantation in rats. Adhesion formation was analyzed in the IPOM position in rabbits. Geometrically identical mono-filamentous polypropylene (PP) Bard Soft

Indexed as

adhesion formationanimal trialsbiocompatibilityIPOMpolyethylene meshultrafine diameter filaments

Identifiers

PMID35740316
PMCPMC9220266
OpenAlexW4281654256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.