Evidence map›Paper›PMID 35740296›Full record

ArticleBiomedicines2022

Modulation of

Saskia Räuber, Maximilian Fischer, Denise Messerer, Vanessa Wimmler, Kumaraswami Konda, Andrei Todica, Michael Lorenz, Anna Titova, Christian Schulz, Tobias Weinberger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Saskia RäuberMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0001-8901-5572
Maximilian FischerMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0001-9172-3316
Denise MessererMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Vanessa WimmlerMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Kumaraswami KondaMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Andrei TodicaDepartment of Nuclear Medicine, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0003-1504-6565
Michael LorenzMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Anna TitovaMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Christian SchulzMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0002-8149-0747
Tobias WeinbergerMedical Clinic I., Department of Cardiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Ludwig-Maximilians-Universität München · DEGerman Centre for Cardiovascular Research · DEHeinrich Heine University Düsseldorf · DE

Funding

Deutsche Stiftung für Herzforschung no grant numberFederal Ministry of Education and Research 81X2600252Federal Ministry of Education and Research 81X2600256Federal Ministry of Education and Research 81Z0600204Friedrich-Baur Stiftung no grant numberLMUexcellent no grant number
6 · The paper itself

Abstract

Retinoid X receptors (RXRs), as members of the steroid/thyroid hormone superfamily of nuclear receptors, are crucial regulators of immune response during health and disease. RXR subtype expression is dependent on tissue and cell type, RXRα being the relevant isoform in monocytes and macrophages. Previous studies have assessed different functions of RXRs and positive implications of RXR agonists on outcomes after ischemic injuries have been described. However, the impact of a reduced

Indexed as

inflammationischemia/reperfusion injurymacrophagesmononuclear phagocytesretinoid receptors

Identifiers

PMID35740296
PMCPMC9219801
OpenAlexW4281672301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.