Evidence map›Paper›PMID 35740227›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications.

Joseph Kusi, Catherine Oluwalopeye Ojewole, Akinloye Emmanuel Ojewole, Isaac Nwi-Mozu

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pathogens (Basel, Switzerland) · 2024
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Dissemination of antimicrobial resistance in surface waters: surveillance of enterococci and coliform bacteria in Slovakia.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Tracking ESBL-ProducingVeterinary sciences · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Prevalence and antimicrobial susceptibility ofOpen veterinary journal · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph KusiDepartment of Environmental Sciences, Southern Illinois University Edwardsville, 44 Circle Drive, Campus Box 1099, Edwardsville, IL 62026, USA.
Catherine Oluwalopeye OjewoleDepartment of Environmental Sciences, Southern Illinois University Edwardsville, 44 Circle Drive, Campus Box 1099, Edwardsville, IL 62026, USA.
Akinloye Emmanuel OjewoleDepartment of Environmental Sciences, Southern Illinois University Edwardsville, 44 Circle Drive, Campus Box 1099, Edwardsville, IL 62026, USA.ORCID 0000-0003-1151-6785
Isaac Nwi-MozuSchmid College of Science and Technology, Chapman University, One University Drive, Orange, CA 92866, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human health is threatened by antibiotic-resistant bacteria and their related infections, which cause thousands of human deaths every year worldwide. Surface waters are vulnerable to human activities and natural processes that facilitate the emergence and spread of antibiotic-resistant bacteria in the environment. This study evaluated the pathways and drivers of antimicrobial resistance (AR) in surface waters. We analyzed antibiotic resistance healthcare-associated infection (HAI) data reported to the CDC's National Healthcare Safety Network to determine the number of antimicrobial-resistant pathogens and their isolates detected in healthcare facilities. Ten pathogens and their isolates associated with HAIs tested resistant to the selected antibiotics, indicating the role of healthcare facilities in antimicrobial resistance in the environment. The analyzed data and literature research revealed that healthcare facilities, wastewater, agricultural settings, food, and wildlife populations serve as the major vehicles for AR in surface waters. Antibiotic residues, heavy metals, natural processes, and climate change were identified as the drivers of antimicrobial resistance in the aquatic environment. Food and animal handlers have a higher risk of exposure to resistant pathogens through ingestion and direct contact compared with the general population. The AR threat to public health may grow as pathogens in aquatic systems adjust to antibiotic residues, contaminants, and climate change effects. The unnecessary use of antibiotics increases the risk of AR, and the public should be encouraged to practice antibiotic stewardship to decrease the risk.

Indexed as

antibioticsaquatic systemsbacteriaphenotypesresistance genesresistant pathogens

Identifiers

PMID35740227
PMCPMC9219700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.