Evidence map›Paper›PMID 35740197›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Effectiveness of Educational Interventions for Health Workers on Antibiotic Prescribing in Outpatient Settings in China: A Systematic Review and Meta-Analysis.

Kunhua Zheng, Ying Xie, Lintao Dan, Meixian Mao, Jie Chen, Ran Li, Xuanding Wang, Therese Hesketh

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kunhua ZhengPeople's Hospital of Kaihua, Quzhou 324300, China.
Ying XieCenter for Global Health, Zhejiang University School of Medicine, Hangzhou 310000, China.ORCID 0000-0002-7941-5772
Lintao DanCenter for Global Health, Zhejiang University School of Medicine, Hangzhou 310000, China.ORCID 0000-0001-5963-2772
Meixian MaoPeople's Hospital of Kaihua, Quzhou 324300, China.
Jie ChenCenter for Global Health, Zhejiang University School of Medicine, Hangzhou 310000, China.ORCID 0000-0002-4029-4192
Ran LiCenter for Global Health, Zhejiang University School of Medicine, Hangzhou 310000, China.
Xuanding WangDepartment of Antimicrobial Stewardship, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China.
Therese HeskethCenter for Global Health, Zhejiang University School of Medicine, Hangzhou 310000, China.

Funding

Pfizer Independent Grants for Learning & Change 41715759
6 · The paper itself

Abstract

Educational interventions are considered an important component of antibiotic stewardship, but their effect has not been systematically evaluated in outpatient settings in China. This research aims to evaluate the effectiveness of educational interventions for health workers on antibiotic prescribing rates in Chinese outpatient settings. Eight databases were searched for relevant randomized clinical trials, non-randomized trials, controlled before-after studies and interrupted time-series studies from January 2001 to July 2021. A total of 16 studies were included in the systematic review and 12 in the meta-analysis. The results showed that educational interventions overall reduced the antibiotic prescription rate significantly (relative risk, RR 0.72, 95% confidence interval, CI 0.61 to 0.84). Subgroup analysis demonstrated that certain features of education interventions had a significant effect on antibiotic prescription rate reduction: (1) combined with compulsory administrative regulations (RR With: 0.65 vs. Without: 0.78); (2) combined with financial incentives (RR With: 0.51 vs. Without: 0.77). Educational interventions can also significantly reduce antibiotic injection rates (RR 0.83, 95% CI 0.74 to 0.94) and the inappropriate use of antibiotics (RR 0.61, 95% CI 0.51 to 0.73). The limited number of high-quality studies limits the validity and reliability of the results. More high-quality educational interventions targeting the reduction of antibiotic prescribing rates are needed.

Indexed as

antibioticsChinaeducational interventionoutpatientresistancestewardship

Identifiers

PMID35740197
PMCPMC9220158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.