Evidence map›Paper›PMID 35740160›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antibacterial and Anti-Inflammatory Properties of a Novel Antimicrobial Peptide Derived from LL-37.

Haiwei Zhuo, Xi Zhang, Maogen Li, Qian Zhang, Yonglan Wang

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Research Progress in Medical Biomaterials for Bone Infections.Journal of functional biomaterials · 2025
    Review
  7. Article
  8. Article
  9. ScymicrosinFrontiers in microbiology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Haiwei ZhuoSchool and Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Xi ZhangSchool and Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Maogen LiSchool and Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Qian ZhangSchool and Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Yonglan WangSchool and Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Tianjin Medical University · CN

Funding

Science & Technology Development Fund of Tianjin Education Commission for Higher Education 2020KJ185
6 · The paper itself

Abstract

Peri-implantitis is a pathological condition involving tissues around dental implants that are characterized by inflammation of the peri-implant mucosa and progressive loss of supporting bone. We found that the antimicrobial peptide KR-12-3 (KRIVKWIKKFLR) derived from LL-37 had antibacterial properties against

Indexed as

anti-inflammatory activityantimicrobial peptidesMC3T3-E1 cellsoral biofilmsRAW264.7 cells

Identifiers

PMID35740160
PMCPMC9220503
OpenAlexW4281663939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.