Evidence map›Paper›PMID 35740115›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Nanostructured Antibiotics and Their Emerging Medicinal Applications: An Overview of Nanoantibiotics.

Shreya Modi, Gajendra Kumar Inwati, Amel Gacem, Shahabe Saquib Abullais, Rajendra Prajapati, Virendra Kumar Yadav, Rabbani Syed, Mohammed S Alqahtani, Krishna Kumar Yadav, Saiful Islam and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
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  4. Unveiling the Antibacterial Efficacy and Mechanistic Insights of MnOInternational journal of molecular sciences · 2025
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  20. A fresh pH-responsive imipenem-loaded nanocarrier againstFrontiers in bioengineering and biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Shreya ModiDepartment of Microbiology, Shri Sarvajanik Science College, Mehsana 384001, India.
Gajendra Kumar InwatiDepartment of Chemistry, HVHP Institute of Post Graduate Studies and Research, Sarva Vishwavidyalaya, Kadi 382715, India.ORCID 0000-0002-8236-9156
Amel GacemDepartment of Physics, Faculty of Sciences, University 20 Août 1955, Skikda 21000, Algeria.ORCID 0000-0001-6956-2544
Shahabe Saquib AbullaisDepartment of Periodontics and Community Dental Sciences, College of Dentistry, King Khalid University, Abha 62529, Saudi Arabia.
Rajendra PrajapatiDepartment of Microbiology, Shri Sarvajanik Science College, Mehsana 384001, India.
Virendra Kumar YadavDepartment of Microbiology-Biosciences, School of Liberal Arts & Sciences, Mody University, Laxmangarh, Sikar, Rajasthan 332311, India.ORCID 0000-0001-5448-7676
Rabbani SyedDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4695-0645
Mohammed S AlqahtaniDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5027-6545
Krishna Kumar YadavFaculty of Science and Technology, Madhyanchal Professional University, Bhopal 462044, India.ORCID 0000-0002-4228-2726
Saiful IslamCivil Engineering Department, College of Engineering, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-5060-0018
Yongtae AhnDepartment of Earth Resources & Environmental Engineering, Hanyang University, 222-Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea.ORCID 0000-0002-7378-9693
Byong-Hun JeonDepartment of Earth Resources & Environmental Engineering, Hanyang University, 222-Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea.ORCID 0000-0002-5478-765X
Hanyang University · KRKing Khalid University · SAKing Saud University · SAKadi Sarva Vishwavidyalaya · INMody University of Science and Technology · INUniversity of Skikda · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial strains resistant to antimicrobial treatments, such as antibiotics, have emerged as serious clinical problems, necessitating the development of novel bactericidal materials. Nanostructures with particle sizes ranging from 1 to 100 nanometers have appeared recently as novel antibacterial agents, which are also known as "nanoantibiotics". Nanomaterials have been shown to exert greater antibacterial effects on Gram-positive and Gram-negative bacteria across several studies. Antibacterial nanofilms for medical implants and restorative matters to prevent bacterial harm and antibacterial vaccinations to control bacterial infections are examples of nanoparticle applications in the biomedical sectors. The development of unique nanostructures, such as nanocrystals and nanostructured materials, is an exciting step in alternative efforts to manage microorganisms because these materials provide disrupted antibacterial effects, including better biocompatibility, as opposed to minor molecular antimicrobial systems, which have short-term functions and are poisonous. Although the mechanism of action of nanoparticles (NPs) is unknown, scientific suggestions include the oxidative-reductive phenomenon, reactive ionic metals, and reactive oxygen species (ROS). Many synchronized gene transformations in the same bacterial cell are essential for antibacterial resistance to emerge; thus, bacterial cells find it difficult to build resistance to nanoparticles. Therefore, nanomaterials are considered as advanced solution tools for the fields of medical science and allied health science. The current review emphasizes the importance of nanoparticles and various nanosized materials as antimicrobial agents based on their size, nature, etc.

Indexed as

antibioticsantimicrobial agentsnanocompositesnanomaterials

Identifiers

PMID35740115
PMCPMC9219893
OpenAlexW4281479561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.