Evidence map›Paper›PMID 35740094›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Genotoxic Assessment of Nutraceuticals Obtained from Agricultural Biowaste: Where Do We "

Giorgia Musto, Valentina Laurenzi, Giuseppe Annunziata, Ettore Novellino, Mariano Stornaiuolo

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Agri-Food Wastes as Natural Source of Bioactive Antioxidants.Antioxidants (Basel, Switzerland) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giorgia MustoDepartment of Pharmacy, University of Naples Federico II, Via Montesano 49, 80131 Naples, Italy.
Valentina LaurenziDepartment of Pharmacy, University of Naples Federico II, Via Montesano 49, 80131 Naples, Italy.
Giuseppe AnnunziataDepartment of Pharmacy, University of Naples Federico II, Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-1922-662X
Ettore NovellinoDepartment of Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Mariano StornaiuoloDepartment of Pharmacy, University of Naples Federico II, Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-2200-5083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several pharmaceutical companies are nowadays considering the use of agri-food waste as alternative raw material for the extraction of bioactive compounds to include in nutraceuticals and food supplements. This recycling activity is encountering the support of authorities, which are alarmed by air, soil and water pollution generated by agricultural waste disposal. Waste reuse has several economic advantages: (i) its low cost; (ii) its abundance; (iii) the high content of bioactive molecule (antioxidants, minerals, fibers, fatty acids); as well as (iv) the financial support received by governments eager to promote eco-compatible and pollution-reducing practices. While nutraceuticals produced from biowaste are becoming popular, products that have been risk-assessed in terms of safety are quite rare. This despite waste biomass, in virtue of its chemical complexity, could, in many cases, mine the overall safety of the final nutraceutical product. In this review, we summarize the scientific results published on genotoxicity risk-assessment of bioactive compounds extracted from agricultural waste. The review depicts a scenario where the risk-assessment of biowaste derived products is still scarcely diffuse, but when available, it confirms the safety of these products, and lets us envisage their future inclusion in the list of botanicals allowed for formulation intended for human consumption.

Indexed as

agricultural by-productsAmes testbiowastecircular economygenotoxicitymicronucleus testnutraceuticalsrecyclingrisk-assessment

Identifiers

PMID35740094
PMCPMC9230180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.