Evidence map›Paper›PMID 35740055›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce-A Comprehensive Review.

Min Shi, Jingyu Gu, Hanjing Wu, Abdur Rauf, Talha Bin Emran, Zidan Khan, Saikat Mitra, Abdullah S M Aljohani, Fahad A Alhumaydhi, Yahya S Al-Awthan and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 212 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Antibiofilm Activity of Essential Oils AgainstFoods (Basel, Switzerland) · 2026
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  11. Review
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  15. Effect of Packaging Materials on Lettuce (International journal of food science · 2026
    Article
  16. Article
  17. Article
  18. A major and stable QTL confers impatiens necrotic spot virus resistance in lettuce cv. Eruption.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  19. Consortium of Lettuce and Beet in Succession to Green Manure Irrigated by Treated Dairy Effluent.Water environment research : a research publication of the Water Environment Federation · 2025
    Article
  20. Assessing the Impact of a NovelJournal of fungi (Basel, Switzerland) · 2025
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 6 countries.

Min ShiFaculty of Veterinary and Agricultural Sciences, School of Agriculture and Food, The University of Melbourne, Parkville, VIC 3010, Australia.
Jingyu GuFaculty of Veterinary and Agricultural Sciences, School of Agriculture and Food, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-1895-1712
Hanjing WuFaculty of Veterinary and Agricultural Sciences, School of Agriculture and Food, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-5521-1476
Abdur RaufDepartment of Chemistry, University of Swabi, Swabi 94640, Pakistan.ORCID 0000-0003-2429-5491
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Zidan KhanDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Saikat MitraDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.ORCID 0000-0002-9502-0252
Abdullah S M AljohaniDepartment of Veterinary of Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraydah 52571, Saudi Arabia.
Fahad A AlhumaydhiDepartment of Medical Laboratories, College of Applied Medical Science, Qassim University, Buraydah 52571, Saudi Arabia.ORCID 0000-0002-0151-8309
Yahya S Al-AwthanDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk 47512, Saudi Arabia.ORCID 0000-0001-8738-8076
Omar BahattabDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk 47512, Saudi Arabia.ORCID 0000-0003-3584-6674
Muthu ThiruvengadamDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea.ORCID 0000-0003-0986-5484
Hafiz A R SuleriaFaculty of Veterinary and Agricultural Sciences, School of Agriculture and Food, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-2450-0830
The University of Melbourne · AUQassim University · SAUniversity of Tabuk · SADaffodil International University · BDInternational Islamic University Chittagong · BDKonkuk University · KRUniversity of Dhaka · BDUniversity of Swabi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from food to other specific uses. There are different types in the lettuce group for consumers to choose from. Additionally, lettuce is an excellent source of bioactive compounds such as polyphenols, carotenoids, and chlorophyll with related health benefits. At the same time, nutrient composition and antioxidant compounds are different between lettuce varieties, especially for green and red lettuce types. The benefit of lettuce consumption depends on its composition, particularly antioxidants, which can function as nutrients. The health benefits rely on their biochemical effect when reaching the bloodstream. Some components can be released from the food matrix and altered in the digestive system. Indeed, the bioaccessibility of lettuce is measuring the quantity of these compounds released from the food matrix during digestion, which is important for health-promoting features. Extraction of bioactive compounds is one of the new trends observed in lettuce and is necessarily used for several application fields. Therefore, this review aims to demonstrate the nutritional value of lettuce and its pharmacological properties. Due to their bioaccessibility and bioavailability, the consumer will be able to comprehensively understand choosing a healthier lettuce diet. The common utilization pattern of lettuce extracted nutrients will also be summarized for further direction.

Indexed as

antioxidantbioactive phytochemicalshealth benefitsLactuca sativa L.nutrients

Identifiers

PMID35740055
PMCPMC9219965
OpenAlexW4282834606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.