Evidence map›Paper›PMID 35740022›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Molecular Mechanisms behind Safranal's Toxicity to HepG2 Cells from Dual Omics.

David Roy Nelson, Ala'a Al Hrout, Amnah Salem Alzahmi, Amphun Chaiboonchoe, Amr Amin, Kourosh Salehi-Ashtiani

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  17. Effect ofIranian journal of basic medical sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 4 countries.

David Roy NelsonCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates.ORCID 0000-0001-8868-5734
Ala'a Al HroutBiology Department, United Arab Emirates University, Al-Ain P.O. Box 15551, United Arab Emirates.
Amnah Salem AlzahmiCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates.
Amphun ChaiboonchoeDivision of Science and Math, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates.
Amr AminBiology Department, United Arab Emirates University, Al-Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0001-8888-1102
Kourosh Salehi-AshtianiCenter for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi P.O. Box 129188, United Arab Emirates.ORCID 0000-0002-6521-5243
New York University Abu Dhabi · AEUnited Arab Emirates University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spice saffron (

Indexed as

cancerDNA damagehepatocellular carcinomahypoxanthinenatural productssaffronsafranal

Identifiers

PMID35740022
PMCPMC9219844
OpenAlexW4281746308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.