ArticleAntioxidants (Basel, Switzerland)2022
Optimized Ultrasound-Assisted Enzymatic Extraction of Phenolic Compounds from
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Evaluation of the Potential Hypoglycemic and Neuroprotective Effects of Rosehip Fruit.Molecules (Basel, Switzerland) · 2026Article
- Green Extraction Strategies for Rose Bioactives: Impacts on Chemical Composition and Anti-Aging Efficacy.ACS omega · 2026Article
- Assessment of Fatty Acid Profile, Mineral Composition, and Antioxidant Activity of Fermented Whey Beverages from Organic Cow and Goat Whey with the Organic Sea Buckthorn or Rosehip Juices.Molecules (Basel, Switzerland) · 2026Article
- Distinctive Behavior and Selective Modulation of PPARγ by Pentacyclic Triterpenoid Pomolic Acid and Hederagenin fromJournal of agricultural and food chemistry · 2026Article
- Optimized Ultrasound-Assisted Extraction RevealsAntioxidants (Basel, Switzerland) · 2026Article
- Enhanced Recovery of Bioactive Compounds fromAntioxidants (Basel, Switzerland) · 2026Article
- Phytochemical composition and bioactivities of Saudi endemic Reseda pentagyna essential oils.Scientific reports · 2026Article
- Untargeted UHPLC-HRMS Metabolomic Profiling ofAntioxidants (Basel, Switzerland) · 2025Article
- The Efficacy of Rosehip Oil Emulsion as a Pro-Healing Herbal Medicine for the Treatment of Induced Mucosal Ulcer (Cell Culture and Experimental Study).Oral health & preventive dentistry · 2025Article
- Enhancing Phenolic Compound Recovery from Grape Pomace Residue: Synergistic Approach of Ultrasound- and Enzyme-Assisted Extraction.ACS omega · 2025Article
- Kinetic Modeling and Biological Activities ofAntioxidants (Basel, Switzerland) · 2025Article
- In Vitro Functional Properties of Rosehips from 'Aurora' Edible Garden Rose's Collection.Foods (Basel, Switzerland) · 2024Article
- Antioxidant, Enzyme Inhibitory, and Protective Effect ofPlants (Basel, Switzerland) · 2024Article
- Unveiling the mechanisms for the development of rosehip-based dermatological products: an updated review.Frontiers in pharmacology · 2024Review
- Determination of Caffeoylquinic Acids Content by UHPLC inPlants (Basel, Switzerland) · 2023Article
- Pomegranate Fruit Cracking during Maturation: From Waste to Valuable Fruits.Foods (Basel, Switzerland) · 2023Article
- The Combination of Untargeted Metabolomics with Response Surface Methodology to Optimize the Functional Potential of Common Duckweed (Antioxidants (Basel, Switzerland) · 2023Article
- Optimization of ultrasonic-assisted extraction of flavonoids fromFrontiers in nutrition · 2023Article
- Phenolic profile,Frontiers in pharmacology · 2023Article
- Biological Activity of Bark Extracts from Northern Red Oak (Plants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two techniques, namely, optimized ultrasound-assisted extraction (UAE) and enzyme-assisted extraction (EAE), were used to promote the extraction of phenolic compounds from the pseudo-fruits of Rosa canina L. (RC). For UAE, an optimization process based on the design of experiment (DoE) principles was used for determining the dependence between three variables (i.e., time of extraction, ultrasound amplitude, and the material-to-water ratio) and the total phenolic content of the samples. For EAE, a 2:1:1 pectinase, cellulase, and hemicellulase enzymatic blend was used as pre-treatment for optimized UAE, inducing a higher total phenolic content. The untargeted phenolic profiling approach revealed a great abundance of lower molecular weight phenolics (1.64 mg Eq./g) in UAE-RC extracts, whilst gallic acid (belonging to hydroxybenzoic acid derivatives) was the most abundant individual compound of both extracts. The unsupervised multivariate statistics clearly discriminated the impact of enzymatic pre-treatment on the phenolic profile of RC pseudo-fruits. Finally, Pearson’s correlation coefficients showed that anthocyanins, phenolic acids, and tyrosol derivatives were those compounds mostly correlated to the in vitro antioxidant potential of the extracts, whilst negative and significant (p < 0.05) correlation coefficients were recorded when considering the enzymatic inhibition activities. The highest enzyme-inhibitory activity has been identified against α-glucosidase, which indicates an antidiabetic effect.
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