ArticleAntioxidants (Basel, Switzerland)2022
Antioxidant Effect of Tyr-Ala Extracted from Zein on INS-1 Cells and Type 2 Diabetes High-Fat-Diet-Induced Mice.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 8 citations in OpenAlex.
- Ginseng-derived GABAFG ameliorates type 2 diabetes mellitus by modulating autophagy-lysosome pathway and gut microbiota.Journal of advanced research · 2025Article
- Causal Relationship Between Glycated Hemoglobin (HbA1c) and Cataract: A Bidirectional Mendelian Randomization Study.Translational vision science & technology · 2025Article
- Functional profiling of synthetic camel milk-derived peptides with implication in glucose transport and diabetes.PloS one · 2025Article
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7 authors at 1 institution in 1 country.
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Abstract
Type 2 diabetes mellitus (T2DM) is associated with an oxidative milieu that often leads to adverse health problems. Bioactive peptides of zein possess outstanding antioxidant activity; however, their effects on hyperglycemia-related oxidative stress remain elusive. In the present study, the dipeptide Tyr-Ala (YA), a functional peptide with typical health benefits, was applied to alleviate oxidative stress in pancreatic islets under hyperglycemic conditions. By detecting viability, antioxidant ability, and insulin secretion in INS-1 cells, YA showed excellent protection of INS-1 cells from H
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