Evidence map›Paper›PMID 35740001›Full record

ArticleAntioxidants (Basel, Switzerland)2022

An In Vitro and In Silico Study of Antioxidant Properties of Curcuminoid

Oscar Forero-Doria, Luis Guzmán, Felipe Jiménez-Aspee, Javier Echeverría, Sergio Wehinger, Claudio Valenzuela, Ramiro Araya-Maturana, Maximiliano Martínez-Cifuentes

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Assessment of Anticancer Properties ofPlants (Basel, Switzerland) · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Oscar Forero-DoriaDepartamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomás, Avenida Carlos Schorr 255, Talca 3460000, Chile.
Luis GuzmánDepartamento de Bioquímica Clínica e Inmunohematología, Facultad de Ciencias de la Salud, Universidad de Talca, P.O. Box 747, Talca 3460000, Chile.
Felipe Jiménez-AspeeInstitute of Nutritional Sciences, Department of Food Biofunctionality, University of Hohenheim, Garbenstrasse 28, 70599 Stuttgart, Germany.ORCID 0000-0002-7285-7033
Javier EcheverríaDepartamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0000-0002-1688-968X
Sergio WehingerThrombosis Research Center, Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, Medical Technology School, Universidad de Talca, Talca 3460000, Chile.ORCID 0000-0001-7021-3544
Claudio ValenzuelaCenter for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.
Ramiro Araya-MaturanaInstituto de Química de Recursos Naturales, Universidad de Talca, P.O. Box 747, Talca 3460000, Chile.ORCID 0000-0002-5082-9146
Maximiliano Martínez-CifuentesDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción 4070371, Chile.ORCID 0000-0003-2959-3164
University of Talca · CLUniversidad de Santiago de Chile · CLUniversidad Santo Tomás · CLUniversity of Concepción · CLUniversity of Hohenheim · DE

Funding

Anillo de Investigación en Ciencia y Tecnología ACT210097Fondo Nacional de Desarrollo Científico y Tecnológico 11170142Fondo Nacional de Desarrollo Científico y Tecnológico 3170757Powered@NLHPC ECM-02
6 · The paper itself

Abstract

In this work, we report the synthesis of curcuminoids with ionic liquid characteristics, obtained by incorporating alkyl-substituted pyridinium moiety rather than one phenyl group through a two-step process. The antioxidant capacity of the obtained compounds was evaluated in vitro by 1,1-diphenyl-picrylhydrazyl (DPPH) free radical scavenging and ferric reducing antioxidant power (FRAP) assays, showing that some derivatives are more potent than curcumin. Pyridine curcuminoids (group 4) and curcuminoid

Indexed as

antioxidantscancercurcuminoidsPabon reactionpyridinium salts

Identifiers

PMID35740001
PMCPMC9219799
OpenAlexW4281685769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.