Evidence map›Paper›PMID 35739899›Full record

ArticleAnimals : an open access journal from MDPI2022

Upper and Lower Airways Evaluation and Its Relationship with Dynamic Upper Airway Obstruction in Racehorses.

Chiara Maria Lo Feudo, Giovanni Stancari, Federica Collavo, Luca Stucchi, Bianca Conturba, Enrica Zucca, Francesco Ferrucci

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Decision Making in Severe Equine Asthma-Diagnosis and Monitoring.Animals : an open access journal from MDPI · 2023
    Review
  3. Equine Respiratory Medicine and Cardiology.Animals : an open access journal from MDPI · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chiara Maria Lo FeudoEquine Sports Medicine Laboratory "Franco Tradati", Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0002-9964-2753
Giovanni StancariVeterinary Teaching Hospital, Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.
Federica CollavoFreelance DVM, Rheinbacher Straße 24, 53919 Weilerswist, Germany.ORCID 0000-0002-6962-5338
Luca StucchiVeterinary Teaching Hospital, Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0002-2056-5426
Bianca ConturbaVeterinary Teaching Hospital, Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.
Enrica ZuccaEquine Sports Medicine Laboratory "Franco Tradati", Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0003-0494-1329
Francesco FerrucciEquine Sports Medicine Laboratory "Franco Tradati", Department of Veterinary Medicine and Animal Sciences, Università Degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0002-7285-9880
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dynamic upper airway obstructions (DUAO) are common in racehorses, but their pathogenetic mechanisms have not been completely clarified yet. Multiple studies suggest that alterations of the pharyngo-laryngeal region visible at resting endoscopy may be predictive of the onset of DUAO, and the development of DUAO may be associated with pharyngeal lymphoid hyperplasia (PLH), lower airway inflammation (LAI) and exercise-induced pulmonary hemorrhage (EIPH). The present study aims to investigate the possible relationship between the findings of a complete resting evaluation of the upper and lower airways and DUAO. In this retrospective study, 360 racehorses (Standardbreds and Thoroughbreds) referred for poor performance or abnormal respiratory noises were enrolled and underwent a diagnostic protocol including resting and high-speed treadmill endoscopy, cytological examination of the bronchoalveolar lavage fluid and radiographic assessment of the epiglottis length. In this population, epiglottis flaccidity was associated with dorsal displacement of the soft palate, while no relationship was detected between DUAO and epiglottis length. No associations were detected between DUAO and PLH, LAI or EIPH. In conclusion, it is likely that epiglottis plays a role in upper airway stability, while airways inflammation does not seem to be involved in the pathogenesis of DUAO.

Indexed as

DUAOdynamic upper airway obstructionequineequine endoscopyequine sports medicinehorseupper airway endoscopyupper respiratory tract

Identifiers

PMID35739899
PMCPMC9219429
OpenAlexW4283070954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.