Evidence map›Paper›PMID 35739882›Full record

ArticleAnimals : an open access journal from MDPI2022

Runs of Homozygosity and Quantitative Trait Locus/Association for Semen Parameters in Selected Chinese and South African Beef Cattle.

Mamokoma Cathrine Modiba, Khathutshelo Agree Nephawe, Jun Wang, Nompilo Hlongwane, Khanyisile Hadebe, Wenfa Lu, Bohani Mtileni

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Analysis of Runs of Homozygosity in Aberdeen Angus Cattle.Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mamokoma Cathrine ModibaCollege of Animal Sciences and Technology, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0003-0141-9703
Khathutshelo Agree NephaweDepartment of Animal Sciences, Tshwane University of Technology, Pretoria 0001, South Africa.
Jun WangCollege of Animal Sciences and Technology, Jilin Agricultural University, Changchun 130118, China.
Nompilo HlongwaneAgricultural Research Council, Biotechnology Platform, Pretoria 0110, South Africa.
Khanyisile HadebeAgricultural Research Council, Biotechnology Platform, Pretoria 0110, South Africa.ORCID 0000-0003-3270-6692
Wenfa LuCollege of Animal Sciences and Technology, Jilin Agricultural University, Changchun 130118, China.
Bohani MtileniDepartment of Animal Sciences, Tshwane University of Technology, Pretoria 0001, South Africa.ORCID 0000-0001-5126-598X

Funding

National Key Research and Development Program of China 2018YFE0122000National Research Council of South Africa 120370
6 · The paper itself

Abstract

In this study, runs of homozygosity (ROH) and quantitative trait locus/association (QTL) for semen parameters in selected Chinese and South African beef cattle breed were estimated. The computed results showed 7516 ROH were observed between classes 0−5 Mb with no ROH observed in classes >40 Mb. Distribution of ROH showed high level of genomic coverage for ANG, NGU, CSI, and BEL breeds. Approximately 13 genomic regions with QTL were controlling sperm motility, sperm concentration, semen volume, sperm count, sperm head abnormalities, sperm tail abnormalities, sperm integrity, and percentage of abnormal sperm traits. Nine candidate genes, CDF9, MARCH1, WDR19, SLOICI, ST7, DOP1B, CFAF9, INHBA, and ADAMTS1, were suggested to be associated with above mentioned QTL traits. The results for inbreeding coefficient showed moderate correlation between FROH vs FHOM at 0.603 and high correlation between FROH 0−5 Mb 0.929, and lowest correlation for 0−>40 Mb 0.400. This study suggested recent inbreeding in CSI, BEL, ANG, BON, SIM, and NGU breeds. Furthermore, it highlighted varied inbreeding levels and identified QTL for semen traits and genes of association. These results can assist in implementation of genetic improvement strategies for bulls and provide awareness and proper guidelines in developing breeding programs.

Indexed as

inbreeding coefficientquantitative trait locus/association and breedsROH

Identifiers

PMID35739882
PMCPMC9219517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.