Evidence map›Paper›PMID 35739629›Full record

ArticlePediatric dermatology2022

Microcystic lymphatic malformation presenting as firm, skin-colored papules of the lips.

John R Edminister, Allison Zarbo, Lauren Seale, Ben J Friedman, Tor Shwayder

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Pediatric dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Dual Clinical Presentation of a Birthmark: A Quiz.Acta dermato-venereologica · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

John R EdministerCollege of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, USA.ORCID https://orcid.org/0000-0001-8949-1851
Allison ZarboDepartment of Dermatology, Henry Ford Health System, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0002-2256-7492
Lauren SealeDepartment of Dermatology, Henry Ford Health System, Detroit, Michigan, USA.
Ben J FriedmanDepartment of Dermatology, Henry Ford Health System, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0002-2266-8197
Tor ShwayderDepartment of Dermatology, Henry Ford Health System, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0001-9531-0164
Henry Ford Health System · USUniversity of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microcystic lymphatic malformation (MiLM), also known as lymphangioma circumscriptum, is a superficial collection of lymphatic vessels measuring <1 cm in the largest diameter, often with a more extensive deeper malformation. It commonly presents as discrete or grouped plaques of clear or hemorrhagic vesicles classically described as "frogspawn"; however, here we describe a case of its unique presentation as firm papules on the lips of a healthy six-year-old child. These skin-colored papules in the absence of vesicles with lymphatic and/or hemorrhagic fluid may not be clinically indicative of MiLM. This case represents a diagnostic challenge due to the unique morphology of pink, fleshy papules as opposed to the clear or hemorrhagic vesicles typically observed in MiLM.

Indexed as

CystsLymphangiomaLymphatic AbnormalitiesBlisterChildHemorrhageHumansLiplaservascular malformation

Identifiers

PMID35739629
PMCPMC10083979
OpenAlexW4283369952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.