Evidence map›Paper›PMID 35739598›Full record

ArticleInternational journal of mental health systems2022

Determinants of effective treatment coverage for major depressive disorder in the WHO World Mental Health Surveys.

Daniel V Vigo, Alan E Kazdin, Nancy A Sampson, Irving Hwang, Jordi Alonso, Laura Helena Andrade, Olatunde Ayinde, Guilherme Borges, Ronny Bruffaerts, Brendan Bunting and 17 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of mental health systems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06500624 (Comparative Efficacy of Escitalopram Monotherapy and Escitalopram in Adjuvant With Pizotifen in Depressive Disorder), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06500624 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparative Efficacy of Escitalopram Monotherapy and Escitalopram in Adjuvant With Pizotifen in Depressive Disorder

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled88ConditionsDepressionArmsPizotifen
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 22 countries.

Daniel V VigoDepartment of Psychiatry, University of British Columbia, UBC Hospital - Detwiller Pavilion, Room 2813, 2255 Wesbrook Mall, UBC Vancouver Campus, Vancouver, BC, V6T 2A1, Canada. daniel.vigo@ubc.ca.
Alan E KazdinDepartment of Psychology, Yale University, 2 Hillhouse Avenue- 208205, New Haven, CT, 06520, USA.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA, 02115, USA.
Irving HwangDepartment of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA, 02115, USA.
Jordi AlonsoIMIM-Hospital del Mar Medical Research Institute, PRBB Building, Doctor Aiguader, 88, 08003, Barcelona, Spain.
Laura Helena AndradeUniversity of São Paulo Medical School, Núcleo de Epidemiologia Psiquiátrica - LIM 23, Rua Dr. Ovidio Pires de Campos, 785, São Paulo, CEP, 05403-010, Brazil.
Olatunde AyindeDepartment of Psychiatry, University College Hospital, University of Ibadan, Ibadan, 5116, PMB, Nigeria.
Guilherme BorgesNational Institute of Psychiatry Ramón de La Fuente Muñiz, Calzada México-Xochimilco, 101, Colonia San Lorenzo Huipulco, 14370, Mexico City, DF, Mexico.
Ronny BruffaertsUniversity Psychiatric Center, University of Louvain - KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
Brendan BuntingSchool of Psychology, Ulster University, College Avenue, Londonderry, BT48 7JL, UK.
Giovanni de GirolamoIstituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia, Italy.
Silvia FlorescuNational School of Public Health, Management and Development, 31 Vaselor Str., 21253, Bucharest, Romania.
Oye GurejeDepartment of Psychiatry, University College Hospital, University of Ibadan, Ibadan, 5116, PMB, Nigeria.
Josep Maria HaroNational School of Public Health, Management and Development, 31 Vaselor Str., 21253, Bucharest, Romania.
Meredith G HarrisSchool of Public Health, The University of Queensland, c/o QCMHR, Locked Bag 500, Archerfield, QLD, 4108, Australia.
Elie G KaramDepartment of Psychiatry & Clinical Psychology, St. George Hospital University Medical Center, Beirut, 166378, Ashrafieh, Lebanon.
Georges KaramDepartment of Psychiatry & Clinical Psychology, St. George Hospital University Medical Center, Beirut, 166378, Ashrafieh, Lebanon.
Viviane Kovess-MasfetyEHESP-School of Public Health, Paris Descartes University, 20 Avenue George Sand La Plaine, 93210, Saint Denis, France.
Sing LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong, China.
Fernando Navarro-MateuMurcia Health Service, C/ Lorca, nº 58. -El Palmar, 30120, Murcia, Spain.
José Posada-VillaColegio Mayor de Cundinamarca University, Calle 28 No. 6-02, 11001000, Bogotá, Colombia.
Kate ScottDepartment of Psychological Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
Juan Carlos StagnaroFaculty of Medicine, University of Buenos Aires, Paraguay 2155, C1121ABG CABA, Buenos Aires, Argentina.
Margreet Ten HaveTrimbos-Instituut, Netherlands Institute of Mental Health and Addiction, Da Costakade 45Postbus 725, 3500, 3521 VS, Utrecht, The Netherlands.
Chi-Shin WuDepartment of Psychiatry, National Taiwan University Hospital & College of Medicine, National Taiwan University, No. 7, Chung-Shan South Road, Taipei, 10002, Taiwan.
Miguel XavierLisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), Nova Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria, 130, 1169-056, Lisbon, Portugal.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA, 02115, USA.
Harvard University · USNational School of Public Health, Management and Professional Development · ROUniversity of Balamand · LBChinese University of Hong Kong · HKDélégation Paris 5 · FRHospital del Mar Research Institute · ESInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXIstituti di Ricovero e Cura a Carattere Scientifico · ITKU Leuven · BENational Taiwan University Hospital · TWPark Centre for Mental Health · AUTrimbos Institute · NLUniversidad Colegio Mayor de Cundinamarca · COUniversidad de Buenos Aires · ARUniversidad de Murcia · ESUniversidade de São Paulo · BRUniversidade Nova de Lisboa · PTUniversity College Hospital, Ibadan · NGUniversity of Ibadan · NGUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost individuals with major depressive disorder (MDD) receive either no care or inadequate care. The aims of this study is to investigate potential determinants of effective treatment coverage.

methodsIn order to examine obstacles to providing or receiving care, the type of care received, and the quality and use of that care in a representative sample of individuals with MDD, we analyzed data from 17 WHO World Mental Health Surveys conducted in 15 countries (9 high-income and 6 low/middle-income). Of 35,012 respondents, 3341 had 12-month MDD. We explored the association of socio-economic and demographic characteristics, insurance, and severity with effective treatment coverage and its components, including type of treatment, adequacy of treatment, dose, and adherence.

resultsHigh level of education (OR = 1.63; 1.19, 2.24), private insurance (OR = 1.62; 1.06, 2.48), and age (30-59yrs; OR = 1.58; 1.21, 2.07) predicted effective treatment coverage for depression in a multivariable logistic regression model. Exploratory bivariate models further indicate that education may follow a dose-response relation; that people with severe depression are more likely to receive any services, but less likely to receive adequate services; and that in low and middle-income countries, private insurance (the only significant predictor) increased the likelihood of receiving effective treatment coverage four times.

conclusionsIn the regression models, specific social determinants predicted effective coverage for major depression. Knowing the factors that determine who does and does not receive treatment contributes to improve our understanding of unmet needs and our ability to develop targeted interventions.

Indexed as

Effective coverageGlobal mental healthMajor depressive disorderMental health servicesMental health systems

Identifiers

PMID35739598
PMCPMC9219212
OpenAlexW4283327050

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.