Evidence map›Paper›PMID 35739556›Full record

Trial reportBMC health services research2022

Cost-effectiveness of a transdiagnostic psychotherapy program for youth with common mental health problems.

Rasmus Trap Wolf, Pia Jeppesen, Mette Maria Agner Pedersen, Louise Berg Puggaard, Mikael Thastum, Niels Bilenberg, Per Hove Thomsen, Wendy K Silverman, Kerstin Jessica Plessen, Simon-Peter Neumer and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rasmus Trap WolfChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark. rasmus.trap.wolf@regionh.dk.
Pia JeppesenChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark.
Mette Maria Agner PedersenChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark.
Louise Berg PuggaardChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark.
Mikael ThastumCentre for the Psychological Treatment of Children and Adolescents, Department of Psychology and Behavioural Sciences, Aarhus BSS, Aarhus University, Aarhus, Denmark.
Niels BilenbergDepartment for Child and Adolescent Psychiatry, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.
Per Hove ThomsenResearch Center at the Department for Child- and Adolescent Psychiatry, Aarhus University Hospital, Skejby, Denmark.
Wendy K SilvermanAnxiety and Mood Disorders Program, Yale Child Study Center, Yale School of Medicine, New Haven, CT, USA.
Kerstin Jessica PlessenChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark.
Simon-Peter NeumerCentre for Child and Adolescent Mental Health, Oslo, Norway.
Christoph U CorrellDepartment of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Anne Katrine PagsbergChild and Adolescent Mental Health Center, Mental Health Services - Capital Region of Denmark, Copenhagen, Denmark.
Dorte Gyrd-HansenDanish Centre for Health Economics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectivesOur objective was to evaluate the cost-effectiveness of the transdiagnostic psychotherapy program Mind My Mind (MMM) for youth with common mental health problems using a cost-utility analysis (CUA) framework and data from a randomized controlled trial. Furthermore, we analyzed the impact of the choice of informant for both quality-of-life reporting and preference weights on the Incremental Cost-Effectiveness Ratio (ICER).

methodsA total of 396 school-aged (6-16 years) youth took part in the 6-month trial carried out in Denmark. CUAs were carried out for the trial period and four one-year extrapolation scenarios. Costs were based on a combination of budget and self-reported costs. Youths and parents were asked to report on the youth's quality-of-life three times during the trial using the Child Health Utility 9D (CHU9D). Parental-reported CHU9D was used in the base case together with preference weights of a youth population. Analyses using self-reported CHU9D and preference weights of an adult population were also carried out.

resultsThe analysis of the trial period resulted in an ICER of €170,465. The analyses of the one-year scenarios resulted in ICERs between €23,653 and €50,480. The ICER increased by 24% and 71% compared to the base case when using self-reported CHU9D and adult preference weights, respectively.

conclusionThe MMM intervention has the potential to be cost-effective, but the ICER is dependent on the duration of the treatment effects. Results varied significantly with the choice of informant and the choice of preference weights indicating that both factors should be considered when assessing CUA involving youth.

Indexed as

Mental HealthQuality of LifeAdolescentAdultChildCost-Benefit AnalysisHumansParentsPsychotherapyQuality-Adjusted Life YearsAdolescentsAnxietyBehavioral problemsChildrenCognitive behavioral interventionCost-effectivenessDepressionInformantPreference weightsTransdiagnostic

Identifiers

PMID35739556
PMCPMC9229821

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.