Evidence map›Paper›PMID 35739534›Full record

Trial reportAIDS research and therapy2022

A pilot pragmatic trial of a "what matters most"-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana.

Lawrence H Yang, Evan L Eschliman, Haitisha Mehta, Supriya Misra, Ohemaa B Poku, Patlo Entaile, Timothy D Becker, Tadele Melese, Merrian J Brooks, Marlene Eisenberg and 14 more

Open access · goldAbstract readPragmatic Clinical Trial
In one paragraph

Trial report in AIDS research and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 13 institutions in 2 countries.

Lawrence H Yang *Department of Social and Behavioral Sciences, School of Global Public Health, New York University, 708 Broadway, New York, NY, 10003, USA. ly1067@nyu.edu.
Evan L Eschliman *Department of Health, Behavior and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Haitisha MehtaDepartment of Clinical and Counseling Psychology, Teachers College, Columbia University, New York, NY, USA.
Supriya MisraDepartment of Public Health, San Francisco State University, San Francisco, CA, USA.
Ohemaa B PokuDivision of Gender, Sexuality, and Health, HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric Institute, New York, NY, USA.
Patlo EntaileBotswana-UPenn Partnership, Gaborone, Botswana.
Timothy D BeckerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Tadele MeleseDepartment of Obstetrics and Gynaecology, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Merrian J BrooksBotswana-UPenn Partnership, Gaborone, Botswana.
Marlene EisenbergDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Melissa A StocktonDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons & New York State Psychiatric Institute, New York, USA.
Karen ChoeDepartment of Clinical and Counseling Psychology, Teachers College, Columbia University, New York, NY, USA.
Danielle TalDepartment of Clinical and Counseling Psychology, Teachers College, Columbia University, New York, NY, USA.
Tingyu LiDepartment of Clinical and Counseling Psychology, Teachers College, Columbia University, New York, NY, USA.
Vivian F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Bruce G LinkSchool of Public Policy, University of California Riverside, Riverside, CA, USA.
Shathani RampaDepartment of Psychology, University of Botswana, Gaborone, Botswana.
Valerie W JacksonDepartment of Anesthesia, University of California San Francisco, San Francisco, CA, USA.
Gorata D ManyeagaeDepartment of Statistics, Faculty of Social Sciences, University of Botswana, Gaborone, Botswana.
Tonya Arscott-MillsDepartment of Pediatrics and Adolescent Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Melody GoodmanDepartment of Biostatistics, School of Global Public Health, New York University, New York, NY, USA.
Philip R OpondoDepartment of Psychiatry, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Ari R Ho-FosterCenter for Global Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Michael B BlankDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
University of Botswana · BWColumbia University · USUniversity of Pennsylvania · USNew York University · USBotswana Open University · BWIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USNew York Psychoanalytic Society and Institute · USNew York State Psychiatric InstituteSan Francisco State University · USUniversity of California, Riverside · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Knashawn Hodge Morales · 2013 to 2026
$23.5M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
Global Mental Health Research Fellowship: Interventions That Make a DifferenceT32MH096724 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2012 to 2026
$4.4M
Global Mental Health Training ProgramT32MH103210 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Judith Karen Bass, Sarah Sutherlin-McIvor Murray · 2015 to 2026
$4.0M
RCT to reduce stigma and improve treatment adherence in HIV+ pregnant women in BotswanaR21TW011084 · FIC · NEW YORK UNIVERSITY · PI YANG, LAWRENCE H · 2018 to 2019
$376k
FIC NIH HHS R21 TW011084NIAID NIH HHS P30 AI045008NIMH NIH HHS P30 MH043520NIMH NIH HHS P30 MH097488NIMH NIH HHS T32 MH019139NIMH NIH HHS T32 MH096724NIMH NIH HHS T32 MH103210
6 · The paper itself

Abstract

We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving 'respected motherhood' ('what matters most') in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = - 1.20; 95% CI - 1.99, - 0.39) and depressive symptoms (d = - 1.96; 95% CI - 2.89, - 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma.

Indexed as

HIV InfectionsBotswanaFemaleHumansPilot ProjectsPregnancySocial StigmaBotswanaCultureIntersectional stigmaPregnant women living with HIVStigma intervention

Identifiers

PMID35739534
PMCPMC9219368
OpenAlexW4283389263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.