ArticleUpdates in surgery2022
Efficiency of ectopic thymectomy by three surgical approaches in non-thymomatous myasthenia gravis.
Article in Updates in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Aberrant malignant invasive thymoma presenting as isolated left internal jugular vein thrombosis.and resected by VATS thymectomy: a case report.Mediastinum (Hong Kong, China) · 2026Article
- Detecting ectopic thymus in thymoma-associated myasthenia gravis through flow cytometry analysis of CD3Annals of medicine and surgery (2012) · 2025Article
- Enigmatic thymus: Variations in anatomical localisation of thymic tissue as an easily misdiagnosed congenital anomaly in surgical practice.World journal of clinical cases · 2024Article
- Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis.Journal of personalized medicine · 2024Review
- Choosing the proper path: outcomes of subxiphoid vs. lateral intercostal approaches in the resection of anterior mediastinal masses.Frontiers in surgery · 2024Article
- Is a subxiphoid approach equivalent to midline sternotomy for extended thymectomy for achieving disease remission in patients with myasthenia gravis?Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Clinical Application of Thoracoscopic Resection of Anterior Mediastinal Tumors under the Xiphoid Process.BioMed research international · 2022Article
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7 authors at 1 institution in 1 country.
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Abstract
backgroundTo explore the efficiency of ectopic thymectomy by the three surgical approaches of trans-sternum, right unilateral thoracoscopy and thoracoscopic subxiphoid in patients with non-thymomatous myasthenia gravis.
methods155 consecutive non-thymomatous myasthenia gravis patients who underwent extended thymectomy by 3 approaches including trans-sternum, right unilateral thoracoscopy and thoracoscopic subxiphoid in 1st affiliated hospital of Sun Yat-Sen University from January 2017 to October 2019 were reviewed. Differences of perioperative clinical characteristics in three surgical approaches were analyzed.
resultsTime to onset of myasthenia gravis (early or late) (p = 0.018), blood loss (p < 0.001), duration of operation (p = 0.031), duration and volume of thoracic drainage (p = 0.039 and p = 0.026), length of hospitalization (p = 0.039), the efficiency of ectopic thymectomy (p = 0.037), and the detection rate of ectopic thymus in the second quadrant (p = 0.018) were different among the three surgical approaches. In univariate logistic regression analysis, higher efficiency of ectopic thymectomy were associated with transsternal (OR 2.36, 95% CI 1.32-4.22, p = 0.011) and thoracoscopic subxiphoid approaches (OR 2.07, 95% CI 1.12-3.82, p = 0.033). In the multiple logistic regression analysis, the transsternal approach (OR 2.02, 95% CI 1.10-3.71, p = 0.024) was an independent protective factor for the efficiency of ectopic thymectomy.
conclusionsBoth the right unilateral thoracoscopic and thoracoscopic subxiphoid approaches have advantages over the transsternal approach in short-term postoperative recovery. Transsternal approach is still the best choice for ectopic thymectomy while thoracoscopic subxiphoid approach show the potential as an alternative way.
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