ReviewPharmaceutical research2022
Recent Developments on Ionic Liquids and Deep Eutectic Solvents for Drug Delivery Applications.
Review in Pharmaceutical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Ciprofloxacin-Based Ionic Liquids Increase Mutation Frequency inAntibiotics (Basel, Switzerland) · 2026Article
- Programmable next-generation supramolecular self-assembled materials as drug delivery systems.Bioactive materials · 2026Review
- Ionic Liquid Pilocarpine Serves as Therapeutic Cosolvent and Permeation Enhancer for Glaucoma Medication.ACS pharmacology & translational science · 2026Article
- Mechanisms of COThe journal of physical chemistry. B · 2025Article
- The Use of Deep Eutectic Solvents for the Synthesis of Iron Oxides Nanoparticles: A Driving Force for Materials Properties.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- An Overview on the Role of Ionic Liquids and Deep Eutectic Solvents in Oral Pharmaceuticals.Pharmaceutics · 2025Review
- Solubilization techniques used for poorly water-soluble drugs.Acta pharmaceutica Sinica. B · 2024Review
- Pharmaceutical applications of therapeutic deep eutectic systems (THEDES) in maximising drug delivery.Heliyon · 2024Review
- Piperacillin/Tazobactam Co-Delivery by Micellar Ionic Conjugate Systems Carrying Pharmaceutical Anions and Encapsulated Drug.Pharmaceutics · 2024Article
- Natural Deep Eutectic Solvents as Rust Removal Agents from Lithic and Cellulosic Substrates.Molecules (Basel, Switzerland) · 2024Article
- Antibacterial and Antioxidant Study of New Pharmaceutical Formulation of Didecyldimethylammonium Bromide Via Pharmaceutical Deep Eutectic Solvents (PDESs) Principle.AAPS PharmSciTech · 2024Article
- Using mandelic acid as an extraction solvent in the extraction of Cu(II) and Cd(II) from soil samples.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023Article
- Polyphenol Iongel Patches with Antimicrobial, Antioxidant and Anti-Inflammatory Properties.Polymers · 2023Article
- Influence of Metal Salts Addition on Physical and Electrochemical Properties of Ethyl and Propylammonium Nitrate.International journal of molecular sciences · 2022Article
- Deep Eutectic Systems as Novel Vehicles for Assisting Drug Transdermal Delivery.Pharmaceutics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The field of Ionic liquids (ILs) and deep eutectic solvents (DESs) is continuously expanding due to their exceptional unique properties and highly tunable nature, which finds applications in broad areas of modern science. Considering numerous possible IL and DES combinations prepared with active pharmaceutical ingredients (APIs), they find applications in pharmaceutical sciences. They can also serve as potential components of drug formulations and hence they have drawn the attention of formulation scientists. Herein, the concept of pharmaceutical ILs and DESs are discussed briefly. The possible applications of these solvent systems for slow drug delivery including nanoscale drug delivery are discussed citing various examples from the published literature. Although the ILs and DESs are found to be suitable for various drug delivery applications but still none of the slow drug delivery vehicles based on these solvents is in practical use. The data relating to long-term toxicity upon administration in the human body followed by various safety evaluations, clinical trials, etc. are pending for such new drug delivery systems. However, proof of concept studies done on the retention of biological activities in the ionic form is quite encouraging and such studies indicate the possibility of application of such new systems in the development of biomedical research and related industries in near future.
Indexed as
Identifiers
35739370What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.