Evidence map›Paper›PMID 35739342›Full record

ArticleNPJ precision oncology2022

Cell graph neural networks enable the precise prediction of patient survival in gastric cancer.

Yanan Wang, Yu Guang Wang, Changyuan Hu, Ming Li, Yanan Fan, Nina Otter, Ikuan Sam, Hongquan Gou, Yiqun Hu, Terry Kwok and 8 more

Abstract read
In one paragraph

Article in NPJ precision oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  14. Self-guided Knowledge-Injected Graph Neural Network for Alzheimer's Diseases.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yanan Wang *Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.
Yu Guang Wang *Institute of Natural Sciences, School of Mathematical Sciences, Key Laboratory of Scientific and Engineering Computing of Ministry of Education (MOE-LSC), and Center for Mathematics of Artificial Intelligence Institute, Shanghai Jiao Tong University, Shanghai, 200240, China.
Changyuan HuBiomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.
Ming LiKey Laboratory of Intelligent Education Technology and Application of Zhejiang Province, Zhejiang Normal University, Jinhua, 321004, China.ORCID http://orcid.org/0000-0002-1218-2804
Yanan FanSchool of Mathematics and Statistics, The University of New South Wales, Sydney, NSW, 2052, Australia.
Nina OtterDepartment of Mathematics, Department of Statistics, University of California, Los Angeles, CA, 90095, USA.
Ikuan SamFaculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
Hongquan GouFaculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
Yiqun HuFaculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
Terry KwokBiomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.
John ZalcbergSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia.
Alex BoussioutasThe Alfred Hospital and Central Clinical School, Monash University, Melbourne, VIC, 3004, Australia.
Roger J DalyBiomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.ORCID http://orcid.org/0000-0002-5739-8027
Guido MontúfarMax Planck Institute for Mathematics in Sciences, Leipzig, 04103, Germany.
Pietro LiòCambridge Centre for AI in Medicine, Department of Computer Science and Technology, University of Cambridge, Cambridge, CB3 0FD, United Kingdom. pl219@cam.ac.uk.ORCID http://orcid.org/0000-0002-0540-5053
Dakang XuFaculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China. dakang_xu@163.com.ORCID http://orcid.org/0000-0003-2415-4920
Geoffrey I WebbDepartment of Data Science and Artificial Intelligence, Monash University, Melbourne, VIC, 3800, Australia. Geoff.Webb@monash.edu.ORCID http://orcid.org/0000-0001-9963-5169
Jiangning SongBiomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia. Jiangning.Song@monash.edu.ORCID http://orcid.org/0000-0001-8031-9086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is one of the deadliest cancers worldwide. An accurate prognosis is essential for effective clinical assessment and treatment. Spatial patterns in the tumor microenvironment (TME) are conceptually indicative of the staging and progression of gastric cancer patients. Using spatial patterns of the TME by integrating and transforming the multiplexed immunohistochemistry (mIHC) images as Cell-Graphs, we propose a graph neural network-based approach, termed Cell-Graph Signature or CG

Identifiers

PMID35739342
PMCPMC9226174

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.