ArticleNature communications2022
Mnemonic construction and representation of temporal structure in the hippocampal formation.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Remembering the "when": Hebbian memory models for the time of past events.PLoS computational biology · 2026Article
- Increasing representational capacity in the hippocampal-frontoparietal system underlies hierarchical development of temporal memory.Developmental cognitive neuroscience · 2026Review
- Article
- Hippocampal representations of temporal structure increase in scale and symmetry across development.bioRxiv : the preprint server for biology · 2026Article
- Entorhinal Cortex Signals Dimensions of Past Experience That Can Be Generalized in a Novel Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Hippocampal relational memory and spatial reconstruction: where are we at and where are we bound?Frontiers in cognition · 2026Review
- From hidden springs to endless oceans: exploring the complementary roles of the amygdala and hippocampus in phenomenal experience.Neuroscience of consciousness · 2026Article
- A Toaster in the Bathroom: Neural Correlates of Semantic Construction During Episodic Memory Recall.Human brain mapping · 2025Article
- The intrinsic time tracker: temporal context is embedded in entorhinal and hippocampal functional connectivity patterns.Nature communications · 2025Article
- Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes.Nature communications · 2025Article
- Shared spectral fingerprints of temporal memory precision and representation of the temporal structure of complex narratives.iScience · 2025Article
- Human neural dynamics of real-world and imagined navigation.Nature human behaviour · 2025Article
- Pattern integration and differentiation: Dual process model of episodic memory.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Integrating and fragmenting memories under stress and alcohol.Neurobiology of stress · 2024Article
- Event Integration and Temporal Differentiation: How Hierarchical Knowledge Emerges in Hippocampal Subfields through Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Theory of mind in mild cognitive impairment and Parkinson's disease: The role of memory impairment.Cognitive, affective & behavioral neuroscience · 2024Article
- Parallel cognitive maps for multiple knowledge structures in the hippocampal formation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Re-expression of CA1 and entorhinal activity patterns preserves temporal context memory at long timescales.Nature communications · 2023Article
- Neural unscrambling of temporal information during a nonlinear narrative.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Goal-oriented representations in the human hippocampus during planning and navigation.Nature communications · 2023Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hippocampal-entorhinal region supports memory for episodic details, such as temporal relations of sequential events, and mnemonic constructions combining experiences for inferential reasoning. However, it is unclear whether hippocampal event memories reflect temporal relations derived from mnemonic constructions, event order, or elapsing time, and whether these sequence representations generalize temporal relations across similar sequences. Here, participants mnemonically constructed times of events from multiple sequences using infrequent cues and their experience of passing time. After learning, event representations in the anterior hippocampus reflected temporal relations based on constructed times. Temporal relations were generalized across sequences, revealing distinct representational formats for events from the same or different sequences. Structural knowledge about time patterns, abstracted from different sequences, biased the construction of specific event times. These findings demonstrate that mnemonic construction and the generalization of relational knowledge combine in the hippocampus, consistent with the simulation of scenarios from episodic details and structural knowledge.
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