Evidence map›Paper›PMID 35738903›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma.

Andreas K Buck, Götz Ulrich Grigoleit, Sabrina Kraus, Andreas Schirbel, Michael Heinsch, Niklas Dreher, Takahiro Higuchi, Constantin Lapa, Heribert Hänscheid, Samuel Samnick and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Is CXCR4 Theranostics in Oncologic, Cardiovascular, and Inflammatory Diseases Really Happening?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  6. Review
  7. Review
  8. Future of radiotheranostics.BMJ oncology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Advances in Radioligand Theranostics in Oncology.Molecular diagnosis & therapy · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. CXCR4-directed PET/CT with [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Article
  20. Theranostics in Hematooncology.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Andreas K BuckDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Götz Ulrich GrigoleitHelios Klinikum Duisburg, Duisburg, Germany.
Sabrina KrausHematology and Oncology, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Andreas SchirbelDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Michael HeinschHelios Klinikum Duisburg, Duisburg, Germany.
Niklas DreherDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Takahiro HiguchiDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Constantin LapaNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany; and.
Heribert HänscheidDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Samuel SamnickDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Hermann EinseleHematology and Oncology, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Sebastian E SerflingDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Rudolf A WernerDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany; werner_r1@ukw.de.
Universitätsklinikum Würzburg · DEBG Klinikum Duisburg · DEJohns Hopkins University · USOkayama University · JPUniversity of Augsburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C motif chemokine receptor 4 (CXCR4)-targeted radioligand therapy (RLT) has already been applied to advanced blood cancers, such as multiple myeloma or diffuse large B-cell lymphoma. We present a series of patients with advanced T-cell lymphoma (TCL) who were scheduled for CXCR4-directed therapy as a conditioning regimen, followed by hematopoietic stem cell transplantation (HSCT).

Indexed as

Hematopoietic Stem Cell TransplantationLymphoma, T-CellLymphoma, T-Cell, PeripheralFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalReceptors, ChemokineReceptors, CXCR4Treatment OutcomeCXCR4 protein, humanReceptors, ChemokineReceptors, CXCR4chemokine receptorC-X-C motif chemokine receptor 4CXCR4radioligand therapyT-cell lymphomatheranostics

Identifiers

PMID35738903
PMCPMC9841250
OpenAlexW4283327273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.