Evidence map›Paper›PMID 35738866›Full record

ArticleSleep2022

Adherence to a healthy sleep pattern and incidence of cardiometabolic multimorbidity among hypertensive patients: a prospective study of UK Biobank.

Lingfang He, Tianqi Ma, Jinchen Li, Yi Luo, Guogang Zhang, Xunjie Cheng, Yongping Bai

Open access · hybridAbstract read
In one paragraph

Article in Sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Sleep and Risk for Heart Disease and Stroke.Arteriosclerosis, thrombosis, and vascular biology · 2026
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  5. [Joint predictive effect of systolic blood pressure variability and sleep patterns on stroke].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lingfang HeDepartment of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.
Tianqi MaDepartment of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-2919-4764
Jinchen LiDepartment of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.
Yi LuoDepartment of Cardiovascular Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Guogang ZhangDepartment of Cardiovascular Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Xunjie ChengDepartment of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.
Yongping BaiDepartment of Geriatric Medicine, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-6355-5842
Central South University · CN

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

STUDY

objectivesTo investigate whether a healthy sleep pattern would reduce the risk of cardiometabolic multimorbidity (CMM) among hypertensives.

methodsThis is a prospective cohort analysis from the UK Biobank. A total of 69 524 hypertensives without a history of diabetes mellitus, coronary heart disease, or stroke at baseline were enrolled. Five dimensions of healthy sleep at baseline including early chronotype, sleep 7-8 h/d, free of insomnia, no snoring, and no frequent excessive daytime sleepiness were used to generate a healthy sleep score ranging from 0 to 5 (one point was given for each dimension of healthy sleep). A higher score indicated a healthier sleep pattern. We set five groups corresponding to the healthy sleep score of 5, 4, 3, 2, and 0-1, respectively. The primary outcome was the incidence of overall CMM among enrolled hypertensives. We assessed the adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) by Fine-Gray subdistribution hazard models.

resultsWe found the full-adjusted HR (95% CI) for overall CMM was 0.93 (0.91-0.95) for a 1-point increase in the healthy sleep score. Compared to hypertensives with a healthy sleep score of 0-1, those with a score of 5 had a 27% lower risk of overall CMM, and 37%, 23%, and 20% lower risks of diabetes mellitus, coronary heart disease, and stroke, respectively, after adjusting for sociodemographic characteristic, lifestyle, and clinical factors.

conclusionsOur results indicated that a healthy sleep pattern was associated with lower risks of CMM outcomes among hypertensives.

Indexed as

Coronary DiseaseDiabetes MellitusHypertensionStrokeBiological Specimen BanksHumansIncidenceMultimorbidityProspective StudiesRisk FactorsSleepUnited Kingdomcardiometabolic multimorbidityhealthy sleep patternhealthy sleep scorehypertensivesUK Biobank

Identifiers

PMID35738866
PMCPMC9548671
OpenAlexW4283385975

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.