Evidence map›Paper›PMID 35738824›Full record

ArticleImmunoHorizons2022

Alboserpin, the Main Salivary Anticoagulant from the Disease Vector

Gaurav Shrivastava, Paola Carolina Valenzuela-Leon, Andrezza Campos Chagas, Olivia Kern, Karina Botello, Yixiang Zhang, Ines Martin-Martin, Markus Berger Oliveira, Lucas Tirloni, Eric Calvo

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Guianensin, aFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Gaurav ShrivastavaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.ORCID 0000-0003-3229-4106
Paola Carolina Valenzuela-LeonLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.ORCID 0000-0002-5740-5178
Andrezza Campos ChagasLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.
Olivia KernLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.ORCID 0000-0003-3577-5423
Karina BotelloLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.
Yixiang ZhangProtein Chemistry Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT; and.ORCID 0000-0003-3422-8436
Ines Martin-MartinLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD.ORCID 0000-0002-0956-7324
Markus Berger OliveiraTick-Pathogen Transmission Unit, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, Hamilton, MT.ORCID 0000-0001-7670-2584
Lucas TirloniTick-Pathogen Transmission Unit, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, Hamilton, MT.ORCID 0000-0003-4582-7100
Eric CalvoLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD; ecalvo@niaid.nih.gov.ORCID 0000-0001-7880-2730
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · US

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
Arthropod saliva in vector-borne disease transmission: Functional analysis of novel domains in salivary secretionsZIAAI001246 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CALVO, ERIC · 2019 to 2025
$10.0M
Tick saliva and its importance for tick feeding and pathogen transmissionZIAAI001337 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI TIRLONI, LUCAS · 2021 to 2025
$8.5M
Investigating the Human Immune Response to Ixodes scapularis Tick BitesZIAAI001333 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARQUES, ADRIANA R · 2021 to 2025
$3.3M
Intramural NIH HHS ZIA AI001246
6 · The paper itself

Abstract

Blood-feeding arthropods secrete potent salivary molecules, which include platelet aggregation inhibitors, vasodilators, and anticoagulants. Among these molecules, Alboserpin, the major salivary anticoagulant from the mosquito vector

Indexed as

AedesAnimalsAnticoagulantsAnti-Inflammatory AgentsCytokinesEndothelial CellsHumansInterleukin-6Mosquito VectorsReceptor, PAR-1AnticoagulantsAnti-Inflammatory AgentsCytokinesInterleukin-6Receptor, PAR-1

Identifiers

PMID35738824
PMCPMC10753553
OpenAlexW4283367637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.