Evidence map›Paper›PMID 35738670›Full record

ArticleAJNR. American journal of neuroradiology2022

Spontaneous Spinal CSF Leaks Stratified by Age, Body Mass Index, and Spinal Level.

M D Mamlouk, P Y Shen, P Jun, M F Sedrak

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Spontaneous intracranial hypotension: A stepwise diagnostic and therapeutic workflow from a tertiary referral center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Updated ultrafast dynamic computed tomography myelography technique for cerebrospinal fluid leaks.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Spinal CSF Leaks: The Neuroradiologist Transforming Care.AJNR. American journal of neuroradiology · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

M D MamloukFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California mark.d.mamlouk@kp.org.ORCID 0000-0002-6689-8912
P Y ShenFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California.ORCID 0000-0002-7657-7186
P JunFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California.ORCID 0000-0002-4757-4728
M F SedrakDepartment of Neurosurgery (M.F.S.), The Permanente Medical Group, Kaiser Permanente Medical Center, Redwood City, Redwood City, California.ORCID 0000-0001-5474-1443
Kaiser Permanente Santa Clara Medical Center · USKaiser Permanente Redwood City Medical Center · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThere are 3 main types of spinal CSF leaks, and the imaging appearances are well-reported. Specific patient demographics and spinal locations of the various types of spinal leaks are less frequently described. The purpose of this article was to stratify the various types of spontaneous CSF leaks on the basis of age, body mass index, and spinal level. MATERIALS AND

methodsRetrospective review was performed for all patients with spontaneous spinal CSF leaks identified on CT myelography. Age, body mass index, and spinal CSF leak type and level were recorded.

resultsSixty-five patients (37 women and 28 men) had spinal CSF leaks. Type 1 CSF leaks (dural tears) were observed in 25 patients (mean age, 44.5 years; mean body mass index, 24.3) and were most common in the upper thoracic spine (72%), particularly at the T1-T2 level (36%). Type 2 CSF leaks (ruptured meningeal diverticula) were observed in 4 patients (mean age, 45.5 years; mean body mass index, 27.5) and were all seen in the lower thoracic spine. Type 3 CSF leaks (CSF-venous fistulas) were observed in 36 patients (mean age, 58.8 years; mean body mass index, 27.0) and were most common on the right side (72%) and in the lower thoracic spine (56%).

conclusionsType 1 CSF leaks occurred in younger patients with a normal body mass index, while patients with type 3 CSF leaks were relatively older and had an elevated body mass index. Type 1 leaks mostly occurred in the upper thoracic spine, and types 2 and 3 leaks mostly occurred in the lower thoracic spine.

Indexed as

DiverticulumIntracranial HypotensionAdultBody Mass IndexCerebrospinal Fluid LeakFemaleHumansMaleMeningesMiddle AgedMyelographySpineTomography, X-Ray Computed

Identifiers

PMID35738670
PMCPMC9262061
OpenAlexW4283392474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.