Evidence map›Paper›PMID 35738631›Full record

ArticleIn vivo (Athens, Greece)

The Modified Glasgow Prognostic Score and Prognostic Nutritional Index as Prognostic Markers in Patients With Metastatic Breast Cancer Treated With Eribulin.

Shinya Yamamoto, Shoko Adachi, Tomoko Wada, Kazutaka Narui, Aki Kimura, Masanori Oshi, Akimitsu Yamada, Toshihiro Misumi, Itaru Endo

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Predicting the Effectiveness of 2 Chemotherapy Regimens Applied to Breast Cancer Patients by Nutritional and Inflammatory Status.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shinya YamamotoDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan; shinya@rf.catv.ne.jp.
Shoko AdachiDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Tomoko WadaDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Kazutaka NaruiDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Aki KimuraDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Masanori OshiDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Akimitsu YamadaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Toshihiro MisumiDepartment of Biostatistics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Itaru EndoDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the role of the Modified Glasgow Prognostic Score (mGPS) and Prognostic Nutritional Index (PNI) as prognostic markers for patients with metastatic breast cancer (MBC). PATIENTS AND

methodsWe investigated the associations of clinico-pathological factors with time-to-treatment failure (TTF) and overall survival (OS) in 110 patients with MBC treated with eribulin.

resultsC-Reactive protein >1 mg/dl, albumin <3.5 g/dl, mGPS=2, and PNI <40 were significant predictors of shorter TTF in univariate analyses. PNI <40 remained a significant and independent predictor of shorter TTF in multivariate analyses. De novo tumor, visceral metastases, C-reactive protein >1 mg/dl, albumin <3.5 g/dl, mGPS=2, and PNI <40 were significant predictors of poor OS at the univariate level. A PNI <40 was a significant and independent predictor of poor OS in multivariate analyses.

conclusionPNI is a reliable predictor of TTF and OS in patients with MBC treated with eribulin.

Indexed as

Breast NeoplasmsNutrition AssessmentC-Reactive ProteinFemaleFuransHumansKetonesPolyether PolyketidesPrognosisRetrospective StudiesC-Reactive ProteineribulinFuransKetonesPolyether PolyketidesBreast cancereribulinmodified Glasgow Prognostic Scoreprognostic markerprognostic nutritional index

Identifiers

PMID35738631
PMCPMC9301441

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.