ArticleIn vivo (Athens, Greece)
Evaluation of Biomechanical Properties and Morphometric Structures of the Trachea in Pigs and Rabbits.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Bench testing a contact sensing tracheal tube for monitoring the cuff-trachea interface.BMC biomedical engineering · 2026Article
- Animal models of benign airway stenosis: Advances in construction techniques, evaluation systems, and perspectives.Animal models and experimental medicine · 2026Review
- Limitations of the porcine model in post-total laryngectomy research.Biomaterials translational · 2026Article
- Towards a bioengineered airway: advances in tracheal tissue engineering and biofabrication.Frontiers in cell and developmental biology · 2026Review
- Airway Malacia: Stent Innovations and Emerging Ex Vivo Testing Platforms.Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual · 2026Review
- Bioengineered tracheal graft with enhanced vascularization and mechanical stability for functional airway reconstruction.Regenerative therapy · 2025Review
- Tissue-engineered tracheal implants: Advancements, challenges, and clinical considerations.Bioengineering & translational medicine · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimAnimals differ in the biochemical composition, attachments, and mechanical properties of tracheal cartilage. This study examined the biomechanical properties and morphological structure of the trachea of pigs, and rabbits as preclinical models. MATERIALS AND
methodsThe trachea in pigs and rabbits can be divided into four regions, cranial cervical, middle cervical, thoracic inlet, and intra-thoracic parts.
resultsThe total number of tracheal rings in pigs and rabbits was 32-35 and 34-38 rings, respectively. The pig bronchus first branches from the trachea, reaching the cranial lobe of the lungs before branching to the main bronchus, while the rabbit bronchus branched after the main bronchus. A comparison of the posterior region of the crosssectional trachea shows that the rabbit has a C-shape with cartilage connected to the tracheal muscle, and the pig has the tracheal muscle covered with cartilage. The trachea of pigs and rabbits decreased in tracheal thickness and size from the thoracic inlet toward the lungs. The stress-strain in the longitudinal and transverse tensile test was higher in rabbits than in pigs. The tensile stress of the four regions was significantly different in the transverse tensile test (p<0.001). In the bending test, more force was required to bend pig than rabbit tracheas. Microscopic and scanning electron microscopy showed no structural differences in tracheal cartilage between the two species.
conclusionThese results suggest that there is great variation in morphology and physical properties of the trachea in pigs and rabbits. We found porcine tracheas have similar biomechanical properties to those of humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.