Evidence map›Paper›PMID 35738168›Full record

ArticleEuropean journal of radiology2022

Neuroimaging in acute ischemic stroke: Trends, disparities, and clinical impact.

Jason J Wang, Jeffrey M Katz, Artem Boltyenkov, Gabriela Martinez, Joseph O'Hara, Michele Gribko, Ankur Pandya, Elizabeth Rula, Pina Sanelli

Open access · greenAbstract read
In one paragraph

Article in European journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jason J WangImaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States; Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States. Electronic address: Jwang11@northwell.edu.
Jeffrey M KatzDepartment of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States; Department of Neurology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States.
Artem BoltyenkovImaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States; Siemens Medical Solutions USA Inc., Malvern, PA; 5 -Harvard T.H Chan School of Public Health, Boston, MA 02115, United States.
Gabriela MartinezImaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States; Siemens Medical Solutions USA Inc., Malvern, PA; 5 -Harvard T.H Chan School of Public Health, Boston, MA 02115, United States.
Joseph O'HaraImaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States.
Michele GribkoDepartment of Neurology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States.
Ankur PandyaThe Harvey L. Neiman Health Policy Institute, Reston, VA, United States.
Elizabeth RulaThe Harvey L. Neiman Health Policy Institute, Reston, VA, United States. Electronic address: erula@neimanhpi.org.
Pina SanelliImaging Clinical Effectiveness and Outcomes Research, Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, United States; Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, United States.
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell · USFeinstein Institute for Medical Research · USHarvey L. Neiman Health Policy Institute · USHealth Outcomes Solutions (United States) · USHealth Economics and Outcomes Research (United Kingdom) · GB

Funding

Comparative Effectiveness of Imaging Strategies in Acute Ischemic Stroke Based on Patient Profiles - Resubmission - 1R56NS114275 · NINDS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SANELLI, PINA CHRISTINE · 2020 to 2020
$628k
NINDS NIH HHS R56 NS114275
6 · The paper itself

Abstract

introductionClinical studies over the past decade expanded the eligibility criteria for endovascular therapy, with advanced imaging selection and new devices leading to higher rates of good outcomes. Herein, we explore the current trends in neuroimaging, associated factors, and impact on treatment and clinical outcomes. MATERIALS AND

methodsThis is a retrospective study of consecutive acute ischemic stroke patients, admitted to a comprehensive stroke center from 2016 to 2020. Patient characteristics, including age, sex, race, arrival method, admission National Institutes of Health Stroke Scale score and last known well to arrival time; imaging and treatment utilization; and discharge outcome by modified Rankin Scale and disposition were extracted from medical records. Trend and multivariable logistic regression analyses were performed, and trends were stratified by patient characteristics.

resultsOf 4,125 acute ischemic stroke episodes, 15.1% received intravenous thrombolysis only, and 7.5% received endovascular thrombectomy from 2016 to 2020. Neuroimaging utilization trends significantly increased for computed tomography angiography (CTA) (48.7% to 75.2%, p < 0.001) and computed tomography perfusion (CTP) (0.26% to 32.9%, p < 0.001), and decreased for magnetic resonance angiography (MRA) (43.2% to 24.7%, p < 0.001). These trends held after adjusting for patient characteristics. Endovascular thrombectomy and intravenous thrombolysis were significantly more common in patients with CTA and CTP (p < 0.0001), and these treatments were associated with good clinical outcomes after controlling for patient characteristics.

conclusionWe found significantly increased trends in CTA and CTP imaging, which were associated with endovascular thrombectomy and intravenous thrombolysis utilization, in acute ischemic stroke patients from 2016 to 2020.

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeHumansNeuroimagingRetrospective StudiesThrombectomyTreatment OutcomeAcute ischemic strokeAngiographyNeuroimagingPerfusionTrends analysis

Identifiers

PMID35738168
PMCPMC9901572
OpenAlexW4283123727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.