ArticleGenome biology and evolution2022
How Can We Resolve Lewontin's Paradox?
Article in Genome biology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Inferring the Landscapes of Mutation and Recombination in the Common Marmoset (Callithrix jacchus) in the Presence of Twinning and Hematopoietic Chimerism.American journal of primatology · 2026Article
- Repeated cases of allopatric divergence and secondary contact in cattail (Typha) speciation.Heredity · 2026Article
- Inferring fine-scale rates of mutation and recombination in the coppery titi monkey (Plecturocebus cupreus).Heredity · 2026Article
- Seasonal fluctuations in fitness result in severe reductions in effective population size.bioRxiv : the preprint server for biology · 2026Article
- Pleistocene demographic histories dominate contemporary genomic diversity in a continental radiation of Himalayan-Hengduan songbirds.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Controlling for life-history traits in vertebrates reveals that effective population size does not affect mutation rate or genome size.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Estimating the Reduction in Genetic Diversity from Background Selection under Non-equilibrium Demography and Partial Selfing.Molecular biology and evolution · 2026Article
- Article
- Inferring Fine-Scale Mutation and Recombination Rate Maps in Aye-Ayes (Ecology and evolution · 2025Article
- Article
- Beyond recombination: Exploring the impact of meiotic frequency on genome-wide genetic diversity.PLoS genetics · 2025Article
- Ocean-Wide Conservation Genomics of Blue Whales Suggest New Northern Hemisphere Subspecies.Molecular ecology · 2025Article
- Mating systems and recombination landscape strongly shape genetic diversity and selection in wheat relatives.Evolution letters · 2024Article
- Previously unmeasured genetic diversity explains part of Lewontin's paradox in abioRxiv : the preprint server for biology · 2024Article
- How does evolution work in superabundant microbes?Trends in microbiology · 2024Review
- Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins.Nature communications · 2024Article
- Half a Century of Controversy: The Neutralist/Selectionist Debate in Molecular Evolution.Genome biology and evolution · 2024Article
- High germline mutation rates, but not extreme population outbreaks, influence genetic diversity in a keystone coral predator.PLoS genetics · 2024Article
- Comparative Population Transcriptomics Provide New Insight into the Evolutionary History and Adaptive Potential of World Ocean Krill.Molecular biology and evolution · 2023Article
- The divergence of mutation rates and spectra across the Tree of Life.EMBO reports · 2023Review
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2 authors.
Funding
Abstract
We discuss the genetic, demographic, and selective forces that are likely to be at play in restricting observed levels of DNA sequence variation in natural populations to a much smaller range of values than would be expected from the distribution of census population sizes alone-Lewontin's Paradox. While several processes that have previously been strongly emphasized must be involved, including the effects of direct selection and genetic hitchhiking, it seems unlikely that they are sufficient to explain this observation without contributions from other factors. We highlight a potentially important role for the less-appreciated contribution of population size change; specifically, the likelihood that many species and populations may be quite far from reaching the relatively high equilibrium diversity values that would be expected given their current census sizes.
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