Evidence map›Paper›PMID 35737673›Full record

ArticlePloS one2022

Awareness of hepatitis B post-exposure prophylaxis among healthcare providers in Wakiso district, Central Uganda.

John Bosco Isunju, Solomon Tsebeni Wafula, Rawlance Ndejjo, Rebecca Nuwematsiko, Pamela Bakkabulindi, Aisha Nalugya, James Muleme, Winnie Kansiime Kimara, Simon P S Kibira, Joana Nakiggala and 4 more

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

John Bosco IsunjuDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Solomon Tsebeni WafulaDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.ORCID 0000-0002-6405-015X
Rawlance NdejjoDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Rebecca NuwematsikoDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Pamela BakkabulindiCenter of Excellence for Maternal New-Born Child Health Care, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Aisha NalugyaDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
James MulemeDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Winnie Kansiime KimaraDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Simon P S KibiraDepartment of Community Health and Behavioural Sciences, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Joana NakiggalaDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Richard K MugambeDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Esther BuregyeyaDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.
Tonny SsekamatteDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.ORCID 0000-0002-8127-6759
Rhoda K WanyenzeDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Science, Makerere University, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare providers (HCPs) are at an elevated occupational health risk of hepatitis B virus infections. Post-exposure prophylaxis (PEP) is one of the measures recommended to avert this risk. However, there is limited evidence of HCPs' awareness of hepatitis B PEP. Therefore, this study aimed to establish awareness of hepatitis B PEP among HCPs in Wakiso, a peri-urban district that surrounds Uganda's capital, Kampala.

methodsA total of 306 HCPs, selected from 55 healthcare facilities (HCFs) were interviewed using a validated structured questionnaire. The data were collected and entered using the Kobo Collect mobile application. Multivariable binary logistic regression was used to establish the factors associated with awareness of hepatitis B PEP.

resultsOf the 306 HCPs, 93 (30.4%) had ever heard about hepatitis B PEP and 16 (5.2%) had ever attended training where they were taught about hepatitis B PEP. Only 10.8% were aware of any hepatitis B PEP options, with 19 (6.2%) and 14 (4.6%) mentioning hepatitis B immunoglobulin (HBIG) and hepatitis B vaccine, respectively as PEP options. Individuals working in the maternity department were less likely to be aware of hepatitis B PEP (AOR = 0.10, 95% CI = 0.02-0.53). There was a positive association between working in a healthcare facility in an urban setting and awareness of hepatitis B PEP (AOR = 5.48, 95% CI = 1.42-21.20). Hepatitis B screening and vaccination were not associated with awareness of PEP.

conclusionsOnly one-tenth of the HCPs were aware of any hepatitis B PEP option. Awareness of hepatitis B PEP is associated with the main department of work and working in a healthcare facility in an urban setting. This study suggests a need to sensitise HCPs, especially those in rural HCFs and maternity wards on hepatitis B PEP. The use of innovative strategies such as e-communication channels, including mobile text messaging might be paramount in bridging the awareness gap.

Indexed as

Hepatitis BHIV InfectionsFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHumansPost-Exposure ProphylaxisPregnancyUganda

Identifiers

PMID35737673
PMCPMC9223339

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.