Evidence map›Paper›PMID 35737209›Full record

ReviewJournal of molecular neuroscience : MN2022

Orthogonal Control of Neuronal Circuits and Behavior Using Photopharmacology.

Rossella Castagna, Dušan Kolarski, Romain Durand-de Cuttoli, Galyna Maleeva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular neuroscience : MN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Light-Controlled Modulation and Analysis of Neuronal Functions.International journal of molecular sciences · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Rossella CastagnaLatvian Institute of Organic Synthesis, Aizkraukles 21, Riga, 1006, Latvia.ORCID http://orcid.org/0000-0002-9284-3165
Dušan KolarskiDWI-Leibniz Institut Für Interaktive Materialien E.V, RWTH Aachen University, Forckenbeckstraße 50, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0002-2077-3225
Romain Durand-de CuttoliNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0003-0240-7608
Galyna MaleevaInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028, Barcelona, Spain. gmalieieva@ibecbarcelona.eu.ORCID http://orcid.org/0000-0002-1379-1521
Allen Institute for Brain Science · USBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESDWI – Leibniz Institute for Interactive Materials · DELatvijas Organiskās Sintēzes Institūts · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last decades, photopharmacology has gone far beyond its proof-of-concept stage to become a bona fide approach to study neural systems in vivo. Indeed, photopharmacological control has expanded over a wide range of endogenous targets, such as receptors, ion channels, transporters, kinases, lipids, and DNA transcription processes. In this review, we provide an overview of the recent progresses in the in vivo photopharmacological control of neuronal circuits and behavior. In particular, the use of small aquatic animals for the in vivo screening of photopharmacological compounds, the recent advances in optical modulation of complex behaviors in mice, and the development of adjacent techniques for light and drug delivery in vivo are described.

Indexed as

Ion ChannelsNeuronsAnimalsMiceIon ChannelsBrain circuitsCircadian rhythmIn vivo photomodulationIn vivo technologyNeuronal receptorsPhotopharmacology

Identifiers

PMID35737209
OpenAlexW4283369156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.