Evidence map›Paper›PMID 35737185›Full record

ArticleTranslational stroke research2023

Dysregulation of the Epitranscriptomic Mark m

Anil K Chokkalla, Kinga Pajdzik, Xiaoyang Dou, Qing Dai, Suresh L Mehta, Vijay Arruri, Raghu Vemuganti

Open access · greenAbstract read
In one paragraph

Article in Translational stroke research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. RNA modifications in peripheral blood are associated with acute coronary syndrome.Journal of molecular and cellular cardiology plus · 2026
    Article
  2. Blood N1-methyladenosine (mCritical care (London, England) · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Advancement of epigenetics in stroke.Frontiers in neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Anil K ChokkallaDepartment of Neurological Surgery, University of Wisconsin, Madison, WI, 53792, USA.
Kinga PajdzikDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Xiaoyang DouDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Qing DaiDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Suresh L MehtaDepartment of Neurological Surgery, University of Wisconsin, Madison, WI, 53792, USA.
Vijay ArruriDepartment of Neurological Surgery, University of Wisconsin, Madison, WI, 53792, USA.
Raghu VemugantiDepartment of Neurological Surgery, University of Wisconsin, Madison, WI, 53792, USA. vemuganti@neurosurgery.wisc.edu.
University of Chicago · USUniversity of Wisconsin–Madison · USNeurological Surgery · USWilliam S. Middleton Memorial Veterans Hospital · US

Funding

Role of RNAs in post-stroke brain damageR35NS132184 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Raghu VEMUGANTI · 2023 to 2026
$4.1M
DNA hydroxymethylation and post stroke brain damageR01NS109459 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI VEMUGANTI, RAGHU · 2018 to 2022
$2.1M
BLRD VA IK6 BX005690NINDS NIH HHS R01 NS109459NINDS NIH HHS R35 NS132184U.S. Department of Veterans Affairs IK6BX005690
6 · The paper itself

Abstract

Methylation of adenosine at N1 position yields N

Indexed as

Ischemic StrokeAnimalsIschemiaMaleMethylationMiceMice, Inbred C57BLTranscriptomeCerebral ischemiam1A demethylaseN 1-methyladenosineRNA methylation

Identifiers

PMID35737185
PMCPMC11884747
OpenAlexW4283322783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.